Organ-specific regulation of ATP7A abundance is coordinated with systemic copper homeostasis
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DOI: 10.1038/s41598-017-11961-z
Abstract: Copper (Cu) is an essential cofactor for various enzymatic activities including mitochondrial electron transport, iron mobilization, and peptide hormone maturation. Consequently, Cu dysregulation is associated with fatal neonatal disease, liver and cardiac dysfunction, and anemia.… read more here.
Keywords: homeostasis; regulation atp7a; atp7a; atp7a abundance ... See more keywords