The Intricacies of NRF2 Regulation in Cancer.
Sign Up to like & getrecommendations! Published in 2021 at "Seminars in cancer biology"
DOI: 10.1016/j.semcancer.2021.05.016
Abstract: The complex role of NRF2 in the context of cancer continues to evolve. As a transcription factor, NRF2 regulates various genes involved in redox homeostasis, protein degradation, DNA repair, and xenobiotic metabolism. As such, NRF2… read more here.
Keywords: protein; nrf2 regulation; intricacies nrf2; cancer ... See more keywords
The neural regulation of cancer
Sign Up to like & getrecommendations! Published in 2019 at "Science"
DOI: 10.1126/science.aaz7776
Abstract: Cancers hijack mechanisms of neural plasticity to promote malignant disease progression Cancer has been called the “emperor of all maladies” (1). An estimated 40% of us will be diagnosed with it at some point in… read more here.
Keywords: cancer; neural regulation; biology; regulation cancer ... See more keywords
CENP-A Regulation and Cancer
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.907120
Abstract: In mammals, CENP-A, a histone H3 variant found in the centromeric chromatin, is critical for faithful chromosome segregation and genome integrity maintenance through cell divisions. Specifically, it has dual functions, enabling to define epigenetically the… read more here.
Keywords: regulation cancer; cenp overexpression; cenp regulation; regulation ... See more keywords
Polycomb-like Proteins in Gene Regulation and Cancer
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DOI: 10.3390/genes14040938
Abstract: Polycomb-like proteins (PCLs) are a crucial group of proteins associated with the Polycomb repressive complex 2 (PRC2) and are responsible for setting up the PRC2.1 subcomplex. In the vertebrate system, three homologous PCLs exist: PHF1… read more here.
Keywords: regulation cancer; gene regulation; like proteins; proteins gene ... See more keywords
Regulation of Cancer Metabolism by Deubiquitinating Enzymes: The Warburg Effect
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22126173
Abstract: Cancer is a disorder of cell growth and proliferation, characterized by different metabolic pathways within normal cells. The Warburg effect is a major metabolic process in cancer cells that affects the cellular responses, such as… read more here.
Keywords: cancer; warburg effect; regulation cancer; cancer metabolism ... See more keywords