Transcriptional Regulation of T Cell Metabolism Reprograming.
Sign Up to like & getrecommendations! Published in 2017 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-94-024-1170-6_3
Abstract: T cell activation, differentiation, and function are tightly regulated by a complex network of transcription factors, epigenetic modifications, and signaling pathways of both TCR and cytokines. Over the past decade, it is increasingly clear that… read more here.
Keywords: regulation cell; immune responses; cell immune; cell ... See more keywords
Regulation of B cell responses by distinct populations of CD4 T cells
Sign Up to like & getrecommendations! Published in 2019 at "Biomedical Journal"
DOI: 10.1016/j.bj.2019.06.002
Abstract: Maturation of B cells in Germinal Centers (GC) is a hallmark in adaptive immunity and the basis of successful vaccines that protect us against lethal infections. Nonetheless, vaccination efficacy is very much reduced in aged… read more here.
Keywords: cell responses; cell; regulation cell; populations cd4 ... See more keywords
CALCIUM REGULATION OF T CELL METABOLISM.
Sign Up to like & getrecommendations! Published in 2020 at "Current opinion in physiology"
DOI: 10.1016/j.cophys.2020.07.016
Abstract: T cells are an essential component of the immune system that provide antigen-specific acute and long lasting immune responses to infections and tumors, ascertain the maintenance of immunological tolerance and, on the flipside, mediate autoimmunity… read more here.
Keywords: calcium regulation; regulation cell; cell metabolism; cell ... See more keywords
The regulation of cell polarity and organ positioning in plants
Sign Up to like & getrecommendations! Published in 2017 at "Mechanisms of Development"
DOI: 10.1016/j.mod.2017.04.182
Abstract: The current proposal aims to investigate the mechanisms by which two steroids, pregnenolone (P5) and progesterone (P4) affect zebrafish embryo development. We showed that pregnenolone promoted cell migration, while progesterone was involved in cell patterning.… read more here.
Keywords: cell polarity; regulation cell; organ positioning; hsd3b2 ... See more keywords
Metabolic regulation of NK cell antiviral functions during cytomegalovirus infection.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of leukocyte biology"
DOI: 10.1093/jleuko/qiad018
Abstract: Natural killer (NK) cells quickly mount cytotoxic responses, produce cytokines, and proliferate in response to infected or transformed cells. Moreover, they can develop memory, with enhanced effector responses following activation, in some cases with antigen-specificity.… read more here.
Keywords: cell; metabolic regulation; infection; regulation cell ... See more keywords
Intermediate Filaments and the Regulation of Cell Motility during Regeneration and Wound Healing.
Sign Up to like & getrecommendations! Published in 2017 at "Cold Spring Harbor perspectives in biology"
DOI: 10.1101/cshperspect.a022046
Abstract: SUMMARYIntermediate filaments (IFs) comprise a diverse group of flexible cytoskeletal structures, the assembly, dynamics, and functions of which are regulated by posttranslational modifications. Characteristically, the expression of IF proteins is specific for tissues, differentiation stages,… read more here.
Keywords: wound healing; regeneration; regulation cell; cell motility ... See more keywords
Metabolic plasticity and regulation of T cell exhaustion
Sign Up to like & getrecommendations! Published in 2022 at "Immunology"
DOI: 10.1111/imm.13575
Abstract: The metabolic reprogramming during T cell activation and differentiation affects T cell fate and immune responses. Cell metabolism may serve as the driving force that induces epigenetic modifications, contributing to regulating T cell differentiation. Persistent… read more here.
Keywords: plasticity regulation; cell; metabolic plasticity; cell exhaustion ... See more keywords
MicroRNA in hormonal mechanisms of regulation of NK cell function
Sign Up to like & getrecommendations! Published in 2017 at "Doklady Biochemistry and Biophysics"
DOI: 10.1134/s160767291703005x
Abstract: We investigated the effect of human chorionic gonadotropin, estriol, leptin, ghrelin, and kisspeptin on the microRNA expression in separated NK cells. All of these hormones are able to effectively modulate the expression of microRNAs both… read more here.
Keywords: biochemistry; microrna hormonal; regulation cell; mechanisms regulation ... See more keywords
Epigenetic regulation of cell fate reprogramming in aging and disease: A predictive computational model
Sign Up to like & getrecommendations! Published in 2018 at "PLoS Computational Biology"
DOI: 10.1371/journal.pcbi.1006052
Abstract: Understanding the control of epigenetic regulation is key to explain and modify the aging process. Because histone-modifying enzymes are sensitive to shifts in availability of cofactors (e.g. metabolites), cellular epigenetic states may be tied to… read more here.
Keywords: regulation cell; model; epigenetic regulation; cofactor ... See more keywords
Regulation of T cell repertoires by commensal microbiota
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2022.1004339
Abstract: The gut microbiota plays an important role in regulating the host immune systems. It is well established that various commensal microbial species can induce the differentiation of CD4+ T helper subsets such as Foxp3+ regulatory… read more here.
Keywords: cell; repertoires commensal; cell repertoires; microbiota ... See more keywords
Epigenetic regulation and T-cell responses in endometriosis – something other than autoimmunity
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.943839
Abstract: Endometriosis is defined as the presence of endometrial-like glands and stroma located outside the uterine cavity. This common, estrogen dependent, inflammatory condition affects up to 15% of reproductive-aged women and is a well-recognized cause of… read more here.
Keywords: cell; cell responses; endometriosis; autoimmunity ... See more keywords