Transcriptional Regulation of T Cell Metabolism Reprograming.
Sign Up to like & getrecommendations! Published in 2017 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-94-024-1170-6_3
Abstract: T cell activation, differentiation, and function are tightly regulated by a complex network of transcription factors, epigenetic modifications, and signaling pathways of both TCR and cytokines. Over the past decade, it is increasingly clear that… read more here.
Keywords: regulation cell; immune responses; cell immune; cell ... See more keywords
Regulation of B cell responses by distinct populations of CD4 T cells
Sign Up to like & getrecommendations! Published in 2019 at "Biomedical Journal"
DOI: 10.1016/j.bj.2019.06.002
Abstract: Maturation of B cells in Germinal Centers (GC) is a hallmark in adaptive immunity and the basis of successful vaccines that protect us against lethal infections. Nonetheless, vaccination efficacy is very much reduced in aged… read more here.
Keywords: cell responses; cell; regulation cell; populations cd4 ... See more keywords
CALCIUM REGULATION OF T CELL METABOLISM.
Sign Up to like & getrecommendations! Published in 2020 at "Current opinion in physiology"
DOI: 10.1016/j.cophys.2020.07.016
Abstract: T cells are an essential component of the immune system that provide antigen-specific acute and long lasting immune responses to infections and tumors, ascertain the maintenance of immunological tolerance and, on the flipside, mediate autoimmunity… read more here.
Keywords: calcium regulation; regulation cell; cell metabolism; cell ... See more keywords
The regulation of cell polarity and organ positioning in plants
Sign Up to like & getrecommendations! Published in 2017 at "Mechanisms of Development"
DOI: 10.1016/j.mod.2017.04.182
Abstract: The current proposal aims to investigate the mechanisms by which two steroids, pregnenolone (P5) and progesterone (P4) affect zebrafish embryo development. We showed that pregnenolone promoted cell migration, while progesterone was involved in cell patterning.… read more here.
Keywords: cell polarity; regulation cell; organ positioning; hsd3b2 ... See more keywords
Regulation of T Cell Signaling and Immune Responses by PTPN22
Sign Up to like & getrecommendations! Published in 2024 at "Molecular and Cellular Biology"
DOI: 10.1080/10985549.2024.2378810
Abstract: Abstract Protein tyrosine phosphatases (PTPs) play central roles in the regulation of cell signaling, organismal development, cellular differentiation and proliferation, and cancer. In the immune system, PTPs regulate the activation, differentiation and effector function of… read more here.
Keywords: cell signaling; regulation cell; cell; ptpn22 regulation ... See more keywords
Metabolic regulation of NK cell antiviral functions during cytomegalovirus infection.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of leukocyte biology"
DOI: 10.1093/jleuko/qiad018
Abstract: Natural killer (NK) cells quickly mount cytotoxic responses, produce cytokines, and proliferate in response to infected or transformed cells. Moreover, they can develop memory, with enhanced effector responses following activation, in some cases with antigen-specificity.… read more here.
Keywords: cell; metabolic regulation; infection; regulation cell ... See more keywords
Regulation of Cell–Nanoparticle Interactions through Mechanobiology
Sign Up to like & getrecommendations! Published in 2024 at "Nano Letters"
DOI: 10.1101/2024.07.07.599665
Abstract: Bio–nano interactions have been extensively explored in nanomedicine to develop selective delivery strategies, reduce systemic toxicity, and minimize therapeutic dosing requirements. To enhance the delivery of nanocarriers to cancer cells and improve the therapeutic efficiency… read more here.
Keywords: delivery; cell nanoparticle; regulation cell; cell ... See more keywords
Intermediate Filaments and the Regulation of Cell Motility during Regeneration and Wound Healing.
Sign Up to like & getrecommendations! Published in 2017 at "Cold Spring Harbor perspectives in biology"
DOI: 10.1101/cshperspect.a022046
Abstract: SUMMARYIntermediate filaments (IFs) comprise a diverse group of flexible cytoskeletal structures, the assembly, dynamics, and functions of which are regulated by posttranslational modifications. Characteristically, the expression of IF proteins is specific for tissues, differentiation stages,… read more here.
Keywords: wound healing; regeneration; regulation cell; cell motility ... See more keywords
Metabolic plasticity and regulation of T cell exhaustion
Sign Up to like & getrecommendations! Published in 2022 at "Immunology"
DOI: 10.1111/imm.13575
Abstract: The metabolic reprogramming during T cell activation and differentiation affects T cell fate and immune responses. Cell metabolism may serve as the driving force that induces epigenetic modifications, contributing to regulating T cell differentiation. Persistent… read more here.
Keywords: plasticity regulation; cell; metabolic plasticity; cell exhaustion ... See more keywords
MicroRNA in hormonal mechanisms of regulation of NK cell function
Sign Up to like & getrecommendations! Published in 2017 at "Doklady Biochemistry and Biophysics"
DOI: 10.1134/s160767291703005x
Abstract: We investigated the effect of human chorionic gonadotropin, estriol, leptin, ghrelin, and kisspeptin on the microRNA expression in separated NK cells. All of these hormones are able to effectively modulate the expression of microRNAs both… read more here.
Keywords: biochemistry; microrna hormonal; regulation cell; mechanisms regulation ... See more keywords
Genetic Regulation of Cell Death: Insights from Autoinflammatory Diseases.
Sign Up to like & getrecommendations! Published in 2025 at "Annual review of immunology"
DOI: 10.1146/annurev-immunol-090222-105848
Abstract: Metazoans have evolved innate antimicrobial defenses that promote cellular survival and proliferation. Countering the inevitable molecular mechanisms by which microbes sabotage these pathways, multicellular organisms rely on an alternative, perhaps more ancient, strategy that is… read more here.
Keywords: death insights; regulation cell; genetic regulation; cell death ... See more keywords