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Published in 2019 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-030-32656-2_17
Abstract: Epigenetics refers to mitotically/meiotically heritable mechanisms that regulate gene transcription without a need for changes in the DNA code. Covalent modifications of DNA, in the form of methylation, and histone post-translational modifications, in the form…
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Keywords:
cancer;
epigenetic regulation;
regulation chromatin;
prostate cancer ... See more keywords
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Published in 2019 at "Current opinion in cell biology"
DOI: 10.1016/j.ceb.2019.02.001
Abstract: Chromatin insulators are DNA-protein complexes that play a crucial role in regulating chromatin organization. Within the past two years, a plethora of genome-wide conformation capture studies have helped reveal that insulators are necessary for proper…
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Keywords:
regulation chromatin;
function regulation;
chromatin insulators;
organization ... See more keywords
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Published in 2017 at "Cold Spring Harbor symposia on quantitative biology"
DOI: 10.1101/sqb.2017.82.033795
Abstract: In eukaryotes, genomic DNA is hierarchically packaged by histones into chromatin on several levels to fit inside the nucleus. As a central-level structure between nucleosomal arrays and higher-order chromatin organizations, the 30-nm chromatin fiber and…
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Keywords:
regulation chromatin;
chromatin;
chromatin fibers;
biology ... See more keywords