Syringic acid demonstrates promising protective effect against tau fibrillization and cytotoxicity through regulation of endoplasmic reticulum stress-mediated pathway as a prelude to Alzheimer's disease.
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DOI: 10.1016/j.ijbiomac.2021.09.173
Abstract: There are several studies reporting that different plant-based metabolites are potential inhibitors of protein amyloid fibrillation. As chemical features of metabolites can regulate protein aggregation process, in the present in vitro investigation, tau protein was… read more here.
Keywords: tau; endoplasmic reticulum; alzheimer disease; regulation endoplasmic ... See more keywords