The open architecture of HD-PTP phosphatase provides new insights into the mechanism of regulation of ESCRT function
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DOI: 10.1038/s41598-017-09467-9
Abstract: HD-PTP is a tumour suppressor phosphatase that controls endocytosis, down-regulation of mitogenic receptors and cell migration. Central to its role is the specific recruitment of critical endosomal sorting complexes required for transport (ESCRTs). However, the… read more here.
Keywords: regulation escrt; escrt function; phosphatase; escrt ... See more keywords