ENPP1’s regulation of extracellular cGAMP is a ubiquitous mechanism of attenuating STING signaling
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2119189119
Abstract: Significance The immune system strikes a careful balance between launching a robust response to threats and avoiding overactivation. The molecule cGAMP is an immunotransmitter that activates innate immunity and signals extracellularly, where it is subject… read more here.
Keywords: extracellular cgamp; regulation extracellular; cgamp; enpp1 regulation ... See more keywords
Roles and Regulation of Extracellular Vesicles in Cardiovascular Mineral Metabolism
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2018.00187
Abstract: Cardiovascular calcification is a multifaceted disease that is a leading independent predictor of cardiovascular morbidity and mortality. Recent studies have identified a calcification-prone population of extracellular vesicles as the putative elementary units of vascular microcalcification… read more here.
Keywords: extracellular vesicles; vesicles cardiovascular; roles regulation; calcification ... See more keywords