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Published in 2023 at "Drug development research"
DOI: 10.1002/ddr.22053
Abstract: Different tissues and organs coordinate to keep glucose levels at homeostasis. However, excessive gluconeogenesis in patients with type 2 diabetes mellitus increases blood glucose and causes dysregulation of homeostasis, which easily induces various diseases. Therefore,…
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Keywords:
regulation gluconeogenesis;
molecules pretranslational;
pretranslational regulation;
natural small ... See more keywords
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Published in 2019 at "Life Sciences"
DOI: 10.1016/j.lfs.2018.12.006
Abstract: Aims: Enhanced hepatic gluconeogenesis is an important cause of hyperglycemia in type 2 diabetes. However, the regulatory mechanisms underlying disordered hepatic gluconeogenesis remains largely unclear. In the present study, we investigated the potential role of…
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Keywords:
regulation gluconeogenesis;
gluconeogenesis;
role hepatic;
mice ... See more keywords
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Published in 2018 at "Annals of the New York Academy of Sciences"
DOI: 10.1111/nyas.13435
Abstract: The coordinated regulation between cellular glucose uptake and endogenous glucose production is indispensable for the maintenance of constant blood glucose concentrations. The liver contributes significantly to this process by altering the levels of hepatic glucose…
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Keywords:
glucose production;
regulation gluconeogenesis;
insulin regulation;
gluconeogenesis ... See more keywords