Regulation of hepatic fibrosis by Carcinoembryonic Antigen-related Cell Adhesion Molecule 1.
Sign Up to like & getrecommendations! Published in 2021 at "Metabolism: clinical and experimental"
DOI: 10.1016/j.metabol.2021.154801
Abstract: OBJECTIVE NAFLD is a complex disease marked by cellular abnormalities leading to NASH. NAFLD patients manifest low hepatic levels of CEACAM1, a promoter of insulin clearance. Consistently, Cc1-/- null mice displayed spontaneous hyperinsulinemia/insulin resistance and… read more here.
Keywords: fibrosis; fibrosis carcinoembryonic; hepatic fibrosis; regulation hepatic ... See more keywords
Regulation of hepatic glucose metabolism in health and disease
Sign Up to like & getrecommendations! Published in 2017 at "Nature Reviews Endocrinology"
DOI: 10.1038/nrendo.2017.80
Abstract: The liver is crucial for the maintenance of normal glucose homeostasis — it produces glucose during fasting and stores glucose postprandially. However, these hepatic processes are dysregulated in type 1 and type 2 diabetes mellitus,… read more here.
Keywords: regulation hepatic; control hepatic; hepatic glucose; glucose metabolism ... See more keywords
Commentary on “Re‐regulation of hepatic stellate cell contraction and cirrhotic portal hypertension by Wnt/β‐catenin signaling via interaction with Gli1”
Sign Up to like & getrecommendations! Published in 2020 at "British Journal of Pharmacology"
DOI: 10.1111/bph.15282
Abstract: Correspondence Ralf Weiskirchen, Institute of Molecular Pathobiochemistry, Experimental GeneTherapy and Clinical Chemistry (IFMPEGKC), RWTH University Hospital Aachen, D52074 Aachen, Germany. Email: [email protected] Funding information Deutsche Forschungsgemeinschaft (SFB/TRR57), Grant/Award Numbers: P13, Q3; Interdisciplinary Centre for Clinical… read more here.
Keywords: contraction cirrhotic; stellate cell; commentary regulation; cell contraction ... See more keywords
Regulation of Hepatic Lipid and Glucose Metabolism by INSP3R1.
Sign Up to like & getrecommendations! Published in 2022 at "Diabetes"
DOI: 10.2337/dbi22-0003
Abstract: With the rising epidemics of obesity and nonalcoholic fatty liver disease (NAFLD) and its downstream consequences including steatohepatitis, cirrhosis, and type 2 diabetes in the U.S. and worldwide, new therapeutic approaches are urgently needed to… read more here.
Keywords: lipid glucose; hepatic lipid; insp3r1; glucagon ... See more keywords
Serotonergic Regulation of Hepatic Energy Metabolism
Sign Up to like & getrecommendations! Published in 2021 at "Endocrinology and Metabolism"
DOI: 10.3803/enm.2021.1331
Abstract: The liver is a vital organ that regulates systemic energy metabolism and many physiological functions. Nonalcoholic fatty liver disease (NAFLD) is the commonest cause of chronic liver disease and end-stage liver failure. NAFLD is primarily… read more here.
Keywords: metabolism; regulation hepatic; energy; metabolism serotonergic ... See more keywords