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Published in 2020 at "Trends in biochemical sciences"
DOI: 10.1016/j.tibs.2020.08.004
Abstract: Histone methylation is central to the regulation of eukaryotic transcription. Here, we review how the histone methylation system itself is regulated. There is substantial evidence that mammalian histone methyltransferases and demethylases are phosphorylated and regulated…
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Keywords:
controlling controllers;
methylation;
controllers regulation;
regulation histone ... See more keywords
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Published in 2020 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2020.597498
Abstract: During oogenesis and fertilization, histone lysine methyltransferases (KMTs) and histone lysine demethylases (KDMs) tightly regulate the methylation of histone H3 on lysine-4 (H3K4me) by adding and removing methyl groups, respectively. Female germline-specific conditional knockout approaches…
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Keywords:
methylation oocyte;
regulation histone;
histone lysine;
function regulation ... See more keywords