Regulation of immune cell signaling by activated protein C
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.3mir0817-338r
Abstract: Innate immune cells are an essential part of the host defense response, promoting inflammation through release of proinflammatory cytokines or formation of neutrophil extracellular traps. While these processes are important for defense against infectious agents… read more here.
Keywords: immune; neutrophil extracellular; activated protein; regulation immune ... See more keywords
Regulation of immune and tissue homeostasis by Drosophila POU factors.
Sign Up to like & getrecommendations! Published in 2019 at "Insect biochemistry and molecular biology"
DOI: 10.1016/j.ibmb.2019.04.003
Abstract: The innate immune system of insects deploys both cellular and humoral reactions in immunocompetent tissues for protection of insects against a variety of infections, including bacteria, fungi, and viruses. Transcriptional regulation of genes encoding antimicrobial… read more here.
Keywords: homeostasis; insects; pou factors; regulation immune ... See more keywords
The regulation of immune tolerance by FOXP3
Sign Up to like & getrecommendations! Published in 2017 at "Nature Reviews Immunology"
DOI: 10.1038/nri.2017.75
Abstract: The proper restraint of the destructive potential of the immune system is essential for maintaining health. Regulatory T (Treg) cells ensure immune homeostasis through their defining ability to suppress the activation and function of other… read more here.
Keywords: tolerance foxp3; immune tolerance; foxp3; regulation immune ... See more keywords
Roquin-dependent gene regulation in immune-mediated diseases and future therapies.
Sign Up to like & getrecommendations! Published in 2022 at "International immunology"
DOI: 10.1093/intimm/dxac059
Abstract: The RNA-binding proteins Roquin-1/2 and Regnase-1 exert essential regulation by controlling proinflammatory mRNA expression to prevent autoimmune disease. More recently, inhibition of this post-transcriptional gene regulatory program has been demonstrated to enable enhanced anti-tumor responses… read more here.
Keywords: gene regulation; regulation; gene; regulation immune ... See more keywords
Oxygen-dependent regulation of immune checkpoint mechanisms
Sign Up to like & getrecommendations! Published in 2018 at "International Immunology"
DOI: 10.1093/intimm/dxy038
Abstract: Immunotherapy of cancer has finally materialized following the success of immune checkpoint blockade. Since down-regulation of immune checkpoint mechanisms is beneficial in cancer treatment, it is important to ask why tumors are infamously filled with… read more here.
Keywords: checkpoint mechanisms; immune checkpoint; regulation immune; checkpoint ... See more keywords
Regulation of the immune response to contact sensitizers by Nrf2
Sign Up to like & getrecommendations! Published in 2022 at "Contact Dermatitis"
DOI: 10.1111/cod.14073
Abstract: The skin is frequently exposed to chemical stress by organic chemicals or metal ions that can directly or indirectly challenge its immune components and may lead to T‐cell‐mediated delayed‐type hypersensitivity reactions. The disruption of the… read more here.
Keywords: contact; immune response; contact sensitizers; regulation immune ... See more keywords
MicroRNA‐mediated regulation of immune responses to intestinal helminth infections
Sign Up to like & getrecommendations! Published in 2017 at "Parasite Immunology"
DOI: 10.1111/pim.12406
Abstract: Intestinal helminth infections are highly prevalent in the developing world, often resulting in chronic infection and inflicting high host morbidity. With the emergence of drug‐resistant parasites, a limited number of chemotherapeutic drugs available and stalling… read more here.
Keywords: mediated regulation; immune responses; intestinal helminth; helminth infections ... See more keywords
Influence of Periodizing Dietary Carbohydrate on Iron Regulation and Immune Function in Elite Triathletes.
Sign Up to like & getrecommendations! Published in 2019 at "International journal of sport nutrition and exercise metabolism"
DOI: 10.1123/ijsnem.2019-0131
Abstract: Sleeping with low carbohydrate (CHO) availability is a dietary strategy that may enhance training adaptation. However, the impact on an athlete's health is unclear. This study quantified the effect of a short-term "sleep-low" dietary intervention… read more here.
Keywords: immune function; elite triathletes; regulation immune; iron regulation ... See more keywords
Disruption in the Regulation of Immune Responses in the Placental Subtype of Preeclampsia
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2018.01659
Abstract: Preeclampsia is a pregnancy-specific disorder, of which one of its major subtypes, the placental subtype is considered a response to an ischemic placental environment, impacting fetal growth and pregnancy outcome. Inflammatory immune responses have been… read more here.
Keywords: immune; placental subtype; immune responses; inflammation ... See more keywords
Copper regulation of immune response and potential implications for treating orthopedic disorders
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2022.1065265
Abstract: Copper is an indispensable trace metal element in human body, and copper deficiency is rare in clinic. However, diseases associated with serum copper deficiency, such as leukopenia, neutropenia, arthritis, osteoporosis, and bone defects, are well… read more here.
Keywords: copper; bone; copper regulation; immune response ... See more keywords
Regulation of Immune Cell Function by PPARs and the Connection with Metabolic and Neurodegenerative Diseases
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms19061575
Abstract: Increasing evidence points towards the existence of a bidirectional interconnection between metabolic disease and neurodegenerative disorders, in which inflammation is linking both together. Activation of members of the peroxisome proliferator-activated receptor (PPAR) family has been… read more here.
Keywords: immune cell; metabolic neurodegenerative; cell function; regulation immune ... See more keywords