ERK1/2-RSK2 Signaling in Regulation of ERα -Mediated Responses.
Sign Up to like & getrecommendations! Published in 2022 at "Endocrinology"
DOI: 10.1210/endocr/bqac106
Abstract: Signaling via extracellular regulated kinase 1/2 (ERK1/2) and p90 ribosomal S6 kinase (RSK), a downstream effector, mediate numerous processes. For example, ERK1/2-RSK signaling is essential for estrogen homeostasis in the mammary gland and uterus to… read more here.
Keywords: erk1 rsk2; estrogen; rsk2 signaling; signaling regulation ... See more keywords
A mitochondria-to-nucleus regulation mediated by the nuclear-translocated mitochondrial lncRNAs
Sign Up to like & getrecommendations! Published in 2025 at "PLOS Genetics"
DOI: 10.1371/journal.pgen.1011580
Abstract: A bidirectional nucleus-mitochondria communication is essential for homeostasis and stress. By acting as critical molecules, the nuclear-encoded lncRNAs (nulncRNAs) have been implicated in the nucleus-to-mitochondria anterograde regulation. However, role of mitochondrial-derived lncRNAs (mtlncRNAs) in the… read more here.
Keywords: nuclear translocated; regulation mediated; mitochondria nucleus; nucleus regulation ... See more keywords
KLF2 in Regulation of NF-κB-Mediated Immune Cell Function and Inflammation
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DOI: 10.3390/ijms18112383
Abstract: KLF2 (Kruppel-like factor 2) is a member of the zinc finger transcription factor family, which critically regulates embryonic lung development, function of endothelial cells and maintenance of quiescence in T-cells and monocytes. It is expressed… read more here.
Keywords: mediated immune; immune cell; regulation mediated; inflammation ... See more keywords
Epigenetic Regulation Mediated by Sphingolipids in Cancer
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DOI: 10.3390/ijms24065294
Abstract: Epigenetic changes are heritable modifications that do not directly affect the DNA sequence. In cancer cells, the maintenance of a stable epigenetic profile can be crucial to support survival and proliferation, and said profile can… read more here.
Keywords: regulation mediated; epigenetic regulation; cancer epigenetic; sphingolipids cancer ... See more keywords