Emodin protects hyperglycemia-induced injury in PC-12 cells by up-regulation of miR-9
Sign Up to like & getrecommendations! Published in 2018 at "Molecular and Cellular Endocrinology"
DOI: 10.1016/j.mce.2018.03.009
Abstract: BACKGROUND Diabetic foot is a severe complication of diabetes mellitus, mainly caused by diabetic peripheral neuropathy. The objective of this study was to investigate the function of emodin (a neuroprotective agent reported previously) in diabetic… read more here.
Keywords: emodin; induced injury; high glucose; regulation mir ... See more keywords
Lycium barbarum polysaccharides alleviate hydrogen peroxide-induced injury by up-regulation of miR-4295 in human trabecular meshwork cells.
Sign Up to like & getrecommendations! Published in 2019 at "Experimental and molecular pathology"
DOI: 10.1016/j.yexmp.2018.12.007
Abstract: Glaucoma is a chronic neurodegenerative disease which produces damage to the optic nerve and causes sightlessness. Current remains lack of effective method for glaucoma. Lycium barbarum polysaccharides (LBPs) have pleiotropic effects on various diseases. However,… read more here.
Keywords: regulation mir; htm cells; lbps; h2o2 ... See more keywords
Quercetin ameliorates lipopolysaccharide-caused inflammatory damage via down-regulation of miR-221 in WI-38 cells.
Sign Up to like & getrecommendations! Published in 2019 at "Experimental and molecular pathology"
DOI: 10.1016/j.yexmp.2019.03.002
Abstract: BACKGROUND Pneumonia is a common respiratory disease in pediatrics. Quercetin is a natural flavonoid widely distributed in many foods and drinks. Herein, we focused our investigation on the possible protective activity of quercetin in lipopolysaccharide… read more here.
Keywords: caused inflammatory; mir 221; lps caused; inflammatory damage ... See more keywords
Down-regulation of miR-15a/b accelerates fibrotic remodelling in the Type 2 diabetic human and mouse heart.
Sign Up to like & getrecommendations! Published in 2017 at "Clinical science"
DOI: 10.1042/cs20160916
Abstract: Aim: Myocardial fibrosis is a well-established cause of increased myocardial stiffness and subsequent diastolic dysfunction in the diabetic heart. The molecular regulators that drive the process of fibrotic events in the diabetic heart are still… read more here.
Keywords: heart; mir 15a; diabetic heart; fibrotic remodelling ... See more keywords
Down-regulation of miR-146b-5p by long noncoding RNA MALAT1 in hepatocellular carcinoma promotes cancer growth and metastasis
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.15640
Abstract: MicroRNAs play an important role in liver cancer genesis and progression. In this study, we identified down-regulation of miR-146b-5p associated with tumor growth, metastasis and poor survival in hepatocellular carcinoma (HCC) patients. miR-146b-5p could suppress… read more here.
Keywords: hepatocellular carcinoma; mir 146b; regulation mir; growth metastasis ... See more keywords
Up-regulation of miR-124 inhibits invasion and proliferation of prostate cancer cells through mediating JAK-STAT3 signaling pathway.
Sign Up to like & getrecommendations! Published in 2020 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_202007_22185
Abstract: Since this article has been suspected of research misconduct and the corresponding authors did not respond to our request to prove originality of data and figures, "Up-regulation of miR-124 inhibits invasion and proliferation of prostate… read more here.
Keywords: invasion proliferation; inhibits invasion; proliferation prostate; regulation mir ... See more keywords
Down-regulation of miR-192 protects against rat ischemia-reperfusion injury after myocardial infarction.
Sign Up to like & getrecommendations! Published in 2020 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_202011_23749
Abstract: Since this article has been suspected of research misconduct and the corresponding authors did not respond to our request to prove originality of data and figures, "Down-regulation of miR-192 protects against rat ischemia-reperfusion injury after… read more here.
Keywords: mir 192; ischemia reperfusion; 192 protects; rat ischemia ... See more keywords
Up-Regulation of miR-130b-3p Activates the PTEN/PI3K/AKT/NF-κB Pathway to Defense against Mycoplasma gallisepticum (HS Strain) Infection of Chicken
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms19082172
Abstract: Mycoplasma gallisepticum (MG) is the pathogen of chronic respiratory disease (CRD), hallmarked by vigorous inflammation in chickens, causing the poultry industry enormous losses. miRNAs have emerged as important regulators of animal diseases. Previous miRNA sequencing… read more here.
Keywords: infection; mycoplasma gallisepticum; 130b activates; mir 130b ... See more keywords
Gambogenic Acid Exerts Antitumor Activity in Hypoxic Multiple Myeloma Cells by Regulation of miR-21
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Cancer"
DOI: 10.7150/jca.19290
Abstract: Hypoxia is an inseparable component of the bone marrow (BM) microenvironment, accounting for aggressive tumor behavior and poor prognosis of multiple myeloma (MM). Gambogenic acid (GNA) has proven to be an attractive option for treatment… read more here.
Keywords: multiple myeloma; gambogenic acid; hypoxia; activity ... See more keywords