Temporal and spatial regulation of mRNA export: Single particle RNA‐imaging provides new tools and insights
Sign Up to like & getrecommendations! Published in 2017 at "BioEssays"
DOI: 10.1002/bies.201600124
Abstract: The transport of messenger RNAs (mRNAs) from the nucleus to cytoplasm is an essential step in the gene expression program of all eukaryotes. Recent technological advances in the areas of RNA‐labeling, microscopy, and sequencing are… read more here.
Keywords: export; mrna export; regulation mrna; spatial regulation ... See more keywords
Regulation of mRNA turnover in cystic fibrosis lung disease
Sign Up to like & getrecommendations! Published in 2017 at "Wiley Interdisciplinary Reviews: RNA"
DOI: 10.1002/wrna.1408
Abstract: Cystic fibrosis (CF) is an autosomal recessive disease due to mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, F508del‐CFTR being the most frequent mutation. The CF lung is characterized by a hyperinflammatory phenotype… read more here.
Keywords: cystic fibrosis; regulation mrna; lung disease; disease ... See more keywords
Regulation of mRNA Translation in Neurons—A Matter of Life and Death
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DOI: 10.1016/j.neuron.2017.09.057
Abstract: Dynamic regulation of mRNA translation initiation and elongation is essential for the survival and function of neural cells. Global reductions in translation initiation resulting from mutations in the translational machinery or inappropriate activation of the… read more here.
Keywords: regulation mrna; death; mrna translation; translation ... See more keywords
Regulation of mRNA decay in E. coli.
Sign Up to like & getrecommendations! Published in 2021 at "Critical reviews in biochemistry and molecular biology"
DOI: 10.1080/10409238.2021.1968784
Abstract: Detailed studies of the Gram-negative model bacterium, Escherichia coli, have demonstrated that post-transcriptional events exert important and possibly greater control over gene regulation than transcription initiation or effective translation. Thus, over the past 30 years, considerable… read more here.
Keywords: decay coli; regulation mrna; mrna decay; decay ... See more keywords
TTP-mediated regulation of mRNA stability in immune cells contributes to adaptive immunity, immune tolerance and clinical applications.
Sign Up to like & getrecommendations! Published in 2021 at "RNA biology"
DOI: 10.1080/15476286.2021.1917185
Abstract: Dendritic cells (DCs) form a sentinel network to induce protective immunity against pathogens or self-tolerance. mRNA stability is an important part of the post-transcriptional regulation (PTR) that controls the maturation and function of DCs. In… read more here.
Keywords: regulation mrna; mrna stability; tolerance; ttp mediated ... See more keywords
Signaling Pathways Involved in the Regulation of mRNA Translation
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DOI: 10.1128/mcb.00070-18
Abstract: ABSTRACT Translation is a key step in the regulation of gene expression and one of the most energy-consuming processes in the cell. In response to various stimuli, multiple signaling pathways converge on the translational machinery… read more here.
Keywords: signaling pathways; regulation mrna; mrna translation; translation ... See more keywords
Regulation of mRNA stability contributes to the function of innate lymphoid cells in various diseases
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1118483
Abstract: Innate lymphoid cells (ILCs) are important subsets of innate immune cells that regulate mucosal immunity. ILCs include natural killer cells, innate lymphoid cells-1 (ILC1s), ILC2s, and ILC3s, which have extremely important roles in the immune… read more here.
Keywords: mrna stability; innate lymphoid; regulation mrna; lymphoid cells ... See more keywords
RNA Binding Proteins and Regulation of mRNA Translation in Erythropoiesis
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2018.00910
Abstract: Control of gene expression in erythropoiesis has to respond to signals that may emerge from intracellular processes or environmental factors. Control of mRNA translation allows for relatively rapid modulation of protein synthesis from the existing… read more here.
Keywords: regulation mrna; binding proteins; rna binding; mrna translation ... See more keywords