Regulation of mTORC1 by the Rag GTPases
Sign Up to like & getrecommendations! Published in 2023 at "Biochemical Society Transactions"
DOI: 10.1042/bst20210038
Abstract: The Rag GTPases are an evolutionarily conserved family that play a crucial role in amino acid sensing by the mammalian target of rapamycin complex 1 (mTORC1). mTORC1 is often referred to as the master regulator… read more here.
Keywords: regulation mtorc1; mtorc1 rag; amino acid; rag ... See more keywords
Arf5-mediated regulation of mTORC1 at the plasma membrane
Sign Up to like & getrecommendations! Published in 2023 at "Molecular Biology of the Cell"
DOI: 10.1091/mbc.e22-07-0302
Abstract: The mechanistic target of rapamycin (mTOR) kinase regulates a major signaling pathway in eukaryotic cells. In addition to regulation of mTORC1 at lysosomes, mTORC1 is also localized at other locations. However, little is known about… read more here.
Keywords: membrane ruffles; mtorc1; regulation mtorc1; membrane ... See more keywords