Cnot8 eliminates naïve regulation networks and is essential for naïve-to-formative pluripotency transition
Sign Up to like & getrecommendations! Published in 2022 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkac236
Abstract: Abstract Mammalian early epiblasts at different phases are characterized by naïve, formative, and primed pluripotency states, involving extensive transcriptome changes. Here, we report that deadenylase Cnot8 of Ccr4-Not complex plays essential roles during the transition… read more here.
Keywords: cnot8 eliminates; pluripotency; regulation networks; cnot8 ... See more keywords
Accurate analytic solution of chemical master equations for gene regulation networks in a single cell.
Sign Up to like & getrecommendations! Published in 2018 at "Physical Review E"
DOI: 10.1103/physreve.97.012412
Abstract: Studying gene regulation networks in a single cell is an important, interesting, and hot research topic of molecular biology. Such process can be described by chemical master equations (CMEs). We propose a Hamilton-Jacobi equation method… read more here.
Keywords: single cell; gene regulation; chemical master; networks single ... See more keywords