Transcription and splicing regulation by NLRC5 shape the interferon response in human pancreatic β cells
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DOI: 10.1126/sciadv.abn5732
Abstract: IFNα is a key regulator of the dialogue between pancreatic β cells and the immune system in early type 1 diabetes (T1D). IFNα up-regulates HLA class I expression in human β cells, fostering autoantigen presentation… read more here.
Keywords: hla class; regulation nlrc5; pancreatic cells; nlrc5 shape ... See more keywords