Abstract 5641: Transcriptional regulation by nuclear deformation
Sign Up to like & getrecommendations! Published in 2024 at "Cancer Research"
DOI: 10.1158/1538-7445.am2024-5641
Abstract: Establishment and maintenance of cell identities requires transcriptional rewiring and modulation of three-dimensional genome organization. The nucleus is subject to constant mechanical forces, both intrinsic from the cytoskeleton and extrinsic, such as compression, confinement, and… read more here.
Keywords: regulation nuclear; transcriptional regulation; deformation; nuclear deformation ... See more keywords
Hepatic metabolic regulation by nuclear factor E4BP4.
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DOI: 10.1530/jme-20-0239
Abstract: Discovered as a b-ZIP transcription repressor 30 years ago, E4 promoter-binding protein 4 (E4BP4) has been shown to play critical roles in immunity, circadian rhythms, and cancer progression. Recent research has highlighted E4BP4 as a… read more here.
Keywords: endocrinology; factor e4bp4; metabolic regulation; hepatic metabolic ... See more keywords
Regulation of nuclear transcription by mitochondrial RNA in endothelial cells
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DOI: 10.7554/elife.86204
Abstract: Chromatin-associated RNAs (caRNAs) form a relatively poorly recognized layer of the epigenome. The caRNAs reported to date are transcribed from the nuclear genome. Here, leveraging a recently developed assay for detection of caRNAs and their… read more here.
Keywords: nuclear genome; regulation nuclear; rna; endothelial cells ... See more keywords