Regulation of RNA editing by intracellular acidification
Sign Up to like & getrecommendations! Published in 2021 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkab157
Abstract: Abstract The hydrolytic deamination of adenosine-to-inosine (A-to-I) by RNA editing is a widespread post-transcriptional modification catalyzed by the adenosine deaminase acting on RNA (ADAR) family of proteins. ADAR-mediated RNA editing modulates cellular pathways involved in… read more here.
Keywords: regulation rna; rna; rna editing; intracellular acidification ... See more keywords
mRNA Regulation by RNA Modifications.
Sign Up to like & getrecommendations! Published in 2023 at "Annual review of biochemistry"
DOI: 10.1146/annurev-biochem-052521-035949
Abstract: Chemical modifications on mRNA represent a critical layer of gene expression regulation. Research in this area has continued to accelerate over the last decade, as more modifications are being characterized with increasing depth and breadth.… read more here.
Keywords: modifications mrna; regulation rna; regulation; mrna regulation ... See more keywords
Regulation of RNA Polymerase I Transcription in Development, Disease, and Aging.
Sign Up to like & getrecommendations! Published in 2018 at "Annual review of biochemistry"
DOI: 10.1146/annurev-biochem-062917-012612
Abstract: Ribosome biogenesis is a complex and highly energy-demanding process that requires the concerted action of all three nuclear RNA polymerases (Pol I-III) in eukaryotes. The three largest ribosomal RNAs (rRNAs) originate from a precursor transcript… read more here.
Keywords: transcription development; transcription; regulation rna; rna polymerase ... See more keywords
Regulation of RNA Polymerase I Stability and Function
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14235776
Abstract: Simple Summary Building ribosomes for cellular protein translation is a massive, energy-consuming undertaking. The process is executed by all cells to replenish the relevant pools of proteins required for cellular functions. Cancer cells are strikingly… read more here.
Keywords: polymerase stability; stability function; transcription; rna polymerase ... See more keywords