Haem oxygenase‐1 up‐regulation by rosiglitazone via ROS‐dependent Nrf2‐antioxidant response elements axis or PPARγ attenuates LPS‐mediated lung inflammation
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DOI: 10.1111/bph.14465
Abstract: Haem oxygenase‐1 (HO‐1) is induced by thiazolidinediones including rosiglitazone and exerts anti‐inflammatory effects in various models. However, the molecular mechanisms underlying rosiglitazone‐induced HO‐1 expression remain largely unknown in human pulmonary alveolar epithelial cells (HPAEpiCs). read more here.
Keywords: haem oxygenase; regulation rosiglitazone; rosiglitazone; oxygenase regulation ... See more keywords