Modulating inflammation through the negative regulation of NF‐κB signaling
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.3mir0817-346rrr
Abstract: Immune system activation is essential to thwart the invasion of pathogens and respond appropriately to tissue damage. However, uncontrolled inflammation can result in extensive collateral damage underlying a diverse range of auto‐inflammatory, hyper‐inflammatory, and neoplastic… read more here.
Keywords: modulating inflammation; inflammation; regulation signaling; immune system ... See more keywords
Neurotrophin Regulation and Signaling in Airway Smooth Muscle.
Sign Up to like & getrecommendations! Published in 2021 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-030-68748-9_7
Abstract: Structural and functional aspects of bronchial airways are key throughout life and play critical roles in diseases such as asthma. Asthma involves functional changes such as airway irritability and hyperreactivity, as well as structural changes… read more here.
Keywords: regulation signaling; neurotrophin regulation; smooth muscle; signaling airway ... See more keywords
Regulation of IL-1 signaling by the decoy receptor IL-1R2
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Molecular Medicine"
DOI: 10.1007/s00109-018-1684-z
Abstract: The pleiotropic cytokine IL-1 mediates its biological functions via association with the signaling receptor IL-1R1. Despite an apparent simplicity in IL-1 signaling activation, multiple negative regulators have been identified. The decoy receptor IL-1R2 (also known… read more here.
Keywords: medicine; receptor 1r2; signaling decoy; regulation signaling ... See more keywords
Regulation of signaling proteins in the brain by light
Sign Up to like & getrecommendations! Published in 2019 at "Progress in Neurobiology"
DOI: 10.1016/j.pneurobio.2019.101638
Abstract: In order to study the role of signaling proteins, such as kinases and GTPases, in brain functions it is necessary to control their activity at the appropriate spatiotemporal resolution and to examine the cellular and… read more here.
Keywords: proteins activity; brain; signaling proteins; regulation signaling ... See more keywords
A Review of Twenty Years of Research on the Regulation of Signaling Pathways by Natural Products in Breast Cancer
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27113412
Abstract: Breast cancer (BC) is the second leading cause of death among women, and it has become a global health issue due to the increasing number of cases. Different treatment options, including radiotherapy, surgery, chemotherapy and… read more here.
Keywords: breast cancer; natural products; signaling pathways; regulation signaling ... See more keywords