Regulation of single-cell genome organization into TADs and chromatin nanodomains
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DOI: 10.1038/s41588-020-00716-8
Abstract: The genome folds into a hierarchy of three-dimensional (3D) structures within the nucleus. At the sub-megabase scale, chromosomes form topologically associating domains (TADs)1–4. However, how TADs fold in single cells remains elusive. Here, we revealed… read more here.
Keywords: single cell; regulation single; cell genome; cell ... See more keywords