Regulation of TGF-β Family Signaling by Inhibitory Smads.
Sign Up to like & getrecommendations! Published in 2017 at "Cold Spring Harbor perspectives in biology"
DOI: 10.1101/cshperspect.a022095
Abstract: Inhibitory Smads (I-Smads) have conserved carboxy-terminal MH2 domains but highly divergent amino-terminal regions when compared with receptor-regulated Smads (R-Smads) and common-partner Smads (co-Smads). Smad6 preferentially inhibits Smad signaling initiated by the bone morphogenetic protein (BMP)… read more here.
Keywords: regulation tgf; smad signaling; smads smads; family signaling ... See more keywords
Repair of Limb Ischemia Is Dependent on Hematopoietic Stem Cell Specific-SHP-1 Regulation of TGF-β1
Sign Up to like & getrecommendations! Published in 2022 at "Arteriosclerosis, Thrombosis, and Vascular Biology"
DOI: 10.1161/atvbaha.122.318205
Abstract: Background: Hematopoietic stem cell (HSC) therapy has shown promise for tissue regeneration after ischemia. Therefore, there is a need to understand mechanisms underlying endogenous HSCs activation in response to ischemic stress and coordination of angiogenesis… read more here.
Keywords: blood; regulation tgf; ischemia; shp ... See more keywords
NK Cell Function Regulation by TGF-β-Induced Epigenetic Mechanisms
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2020.00311
Abstract: TGF-β is a potent immunosuppressive cytokine that severely affects the function of NK cells. Tumor cells can take advantage of this ability, enriching their surrounding microenvironment with TGF-β. TGF-β can alter the expression of effector… read more here.
Keywords: regulation tgf; cell function; epigenetic mechanisms; tgf ... See more keywords