The NRF2/KEAP1 Axis in the Regulation of Tumor Metabolism: Mechanisms and Therapeutic Perspectives
Sign Up to like & getrecommendations! Published in 2020 at "Biomolecules"
DOI: 10.3390/biom10050791
Abstract: The NRF2/KEAP1 pathway is a fundamental signaling cascade that controls multiple cytoprotective responses through the induction of a complex transcriptional program that ultimately renders cancer cells resistant to oxidative, metabolic and therapeutic stress. Interestingly, accumulating… read more here.
Keywords: regulation tumor; keap1 axis; nrf2 keap1; tumor metabolism ... See more keywords
The Roles of Epigenetic Regulation and the Tumor Microenvironment in the Mechanism of Resistance to Systemic Therapy in Hepatocellular Carcinoma
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DOI: 10.3390/ijms24032805
Abstract: Primary liver cancer is the sixth most common cancer and the third most common cause of cancer-related deaths worldwide. Hepatocellular carcinoma (HCC) is a major histologic type with a poor prognosis owing to the difficulty… read more here.
Keywords: hepatocellular carcinoma; epigenetic regulation; regulation tumor; tumor microenvironment ... See more keywords
Research progress on the circRNA-mediated regulation of tumor angiogenesis through ceRNA mechanisms
Sign Up to like & getrecommendations! Published in 2022 at "Oncology Reports"
DOI: 10.3892/or.2022.8449
Abstract: Tumors are one of the most common fatal diseases worldwide and pose a severe threat to human health. Effective tumor prevention and treatment strategies are persistent challenges in the medical community. Angiogenesis plays a critical… read more here.
Keywords: regulation tumor; angiogenesis; tumor; tumor angiogenesis ... See more keywords