Mycobacterium tuberculosis TetR family transcriptional regulator Rv1019 is a negative regulator of the mfd‐mazG operon encoding DNA repair proteins
Sign Up to like & getrecommendations! Published in 2020 at "FEBS Letters"
DOI: 10.1002/1873-3468.13861
Abstract: Rv1019, a member of an uncharacterized tetracycline resistance regulator family of transcriptional regulators of Mycobacterium tuberculosis H37Rv, was found to be differentially expressed during dormancy and reactivation in vitro. In this study, we show that… read more here.
Keywords: rv1019; family transcriptional; dna; mazg ... See more keywords
Mammalian D‐cysteine: A novel regulator of neural progenitor cell proliferation
Sign Up to like & getrecommendations! Published in 2022 at "BioEssays"
DOI: 10.1002/bies.202200002
Abstract: D‐amino acids are being recognized as functionally important molecules in mammals. We recently identified endogenous D‐cysteine in mammalian brain. D‐cysteine is present in neonatal brain in substantial amounts (mM) and decreases with postnatal development. D‐cysteine… read more here.
Keywords: cell; proliferation; neural progenitor; regulator ... See more keywords
Rab34 plays a critical role as a bidirectional regulator of osteoclastogenesis
Sign Up to like & getrecommendations! Published in 2022 at "Cell Biochemistry and Function"
DOI: 10.1002/cbf.3691
Abstract: Accumulating evidence suggests that Rab GTPases representing the largest branch of Ras superfamily have recently emerged as the core factors for the regulation of osteoclastogenesis through modulating vesicular transport amongst specific subcellular compartments. Among these,… read more here.
Keywords: osteoclast differentiation; role; osteoclastogenesis; regulator ... See more keywords
The TLR‐chaperone CNPY3 is a critical regulator of NLRP3‐inflammasome activation
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Immunology"
DOI: 10.1002/eji.202149612
Abstract: TLRs mediate the recognition of microbial and endogenous insults to orchestrate the inflammatory response. TLRs localize to the plasma membrane or endomembranes, depending on the member, and rely critically on ER‐resident chaperones to mature and… read more here.
Keywords: role cnpy3; cnpy3; inflammasome activation; tlrs ... See more keywords
A novel LysR‐type regulator negatively affects biosynthesis of the immunosuppressant brasilicardin
Sign Up to like & getrecommendations! Published in 2021 at "Engineering in Life Sciences"
DOI: 10.1002/elsc.202000038
Abstract: Brasilicardin A (BraA) is a promising immunosuppressive compound produced naturally by the pathogenic bacterium Nocardia terpenica IFM 0406. Heterologous host expression of brasilicardin gene cluster showed to be efficient to bypass the safety issues, low… read more here.
Keywords: bra bgc; brasilicardin; lysr type; gene ... See more keywords
Renormalized Volume
Sign Up to like & getrecommendations! Published in 2017 at "Communications in Mathematical Physics"
DOI: 10.1007/s00220-017-2920-z
Abstract: We develop a universal distributional calculus for regulated volumes of metrics that are suitably singular along hypersurfaces. When the hypersurface is a conformal infinity we give simple integrated distribution expressions for the divergences and anomaly… read more here.
Keywords: regulator; renormalized volume; volume;
Biochemical characterization of ferric uptake regulator (Fur) from Aliivibrio salmonicida. Mapping the DNA sequence specificity through binding studies and structural modelling
Sign Up to like & getrecommendations! Published in 2020 at "Biometals"
DOI: 10.1007/s10534-020-00240-6
Abstract: Iron is an essential nutrient for bacteria, however its propensity to form toxic hydroxyl radicals at high intracellular concentrations, requires its acquisition to be tightly regulated. Ferric uptake regulator (Fur) is a metal-dependent DNA-binding protein… read more here.
Keywords: ferric uptake; aliivibrio salmonicida; uptake regulator; regulator fur ... See more keywords
Melatonin, an ubiquitous metabolic regulator: functions, mechanisms and effects on circadian disruption and degenerative diseases
Sign Up to like & getrecommendations! Published in 2020 at "Reviews in Endocrine and Metabolic Disorders"
DOI: 10.1007/s11154-020-09570-9
Abstract: The last four decades, we assist to an increasing scientific interest on melatonin, a circadian hormone, a metabolic regulator which influences not only plants’ metabolism and their defense against pathogens but mostly the animals and… read more here.
Keywords: metabolic regulator; diseases melatonin; circadian disruption; degenerative diseases ... See more keywords
A Selectable Discrete-Voltage Output and Fast-Settling Low-Dropout Regulator Using Half Digitally-Assistant Voltage Accelerator
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Signal Processing Systems"
DOI: 10.1007/s11265-016-1205-7
Abstract: This paper presents a selectable discrete-voltage output and fast-settling low-dropout regulator (LDO) by using half digitally-assistant voltage accelerator. The transition response time within reference switching and transient load regulation is significantly reduced by utilizing the… read more here.
Keywords: half digitally; voltage; discrete voltage; assistant voltage ... See more keywords
Failure of a Pressure Regulator System by Crevice Corrosion: Attributed to Improper Material Selection
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Failure Analysis and Prevention"
DOI: 10.1007/s11668-020-01069-4
Abstract: A pressure regulator in a system of the base shroud failed during service. The pressure regulator is intended to regulate the inlet pressure of 275 to 50 kg/cm2 outlet pressure. The working medium is stated… read more here.
Keywords: system; pressure regulator; surface; failure ... See more keywords
Warm Forming Behavior of Magnesium Alloy Sheet in Manufacturing of Window Regulator Rail
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Automotive Technology"
DOI: 10.1007/s12239-019-0129-1
Abstract: Recently, as the demands to improve automotive fuel efficiency grow, several attempts are being conducted on the development of lightweight automotive components using magnesium (Mg) alloy sheets having the highest specific strength among metal materials.… read more here.
Keywords: alloy; warm forming; forming behavior; rail ... See more keywords