Elevated expression of sepiapterin reductase, regulator of G protein signaling 1, hypothetical protein CXorf58 homolog, and zinc finger and BTB domain-containing protein 21 isoform X2 is associated with progression of hepatocellular carcinoma.
Sign Up to like & getrecommendations! Published in 2021 at "Protoplasma"
DOI: 10.1007/s00709-021-01632-2
Abstract: Hepatocellular carcinoma (HCC) is one of the most common cancers associated with high mortality rate. Understanding of events leading to HCC pathophysiology is essential for its better management. We earlier reported development of a novel… read more here.
Keywords: protein; regulator protein; hepatocellular carcinoma; sepiapterin reductase ... See more keywords
Regulator of G protein signaling 10: Structure, expression and functions in cellular physiology and diseases.
Sign Up to like & getrecommendations! Published in 2020 at "Cellular signalling"
DOI: 10.1016/j.cellsig.2020.109765
Abstract: Regulator of G protein signaling 10 (RGS10) belongs to the superfamily of RGS proteins, defined by the presence of a conserved RGS domain that canonically binds and deactivates heterotrimeric G-proteins. RGS proteins act as GTPase… read more here.
Keywords: regulator protein; protein signaling; physiology; expression ... See more keywords
Oligopeptide models of the metal binding loop of the bacterial copper efflux regulator protein CueR as potential Cu(I) chelators
Sign Up to like & getrecommendations! Published in 2017 at "Inorganica Chimica Acta"
DOI: 10.1016/j.ica.2017.06.062
Abstract: Abstract Copper(I) binding features of oligopeptides, mimicking the metal binding loops (MBL) of the bacterial copper efflux regulator protein CueR, were investigated with an aim of exploring potential candidates for Cu(I)-sequestration. Two of the studied… read more here.
Keywords: regulator protein; copper efflux; copper; metal binding ... See more keywords
Interacting partners of Brassica juncea regulator of G-protein signaling protein suggest its role in cell wall metabolism and cellular signaling
Sign Up to like & getrecommendations! Published in 2022 at "Bioscience Reports"
DOI: 10.1042/bsr20220302
Abstract: Abstract Heterotrimeric G-proteins interact with various upstream and downstream effectors to regulate various aspects of plant growth and development. G-protein effectors have been recently reported in Arabidopsis thaliana; however, less information is available from polyploid… read more here.
Keywords: cell; cell wall; regulator protein; brassica juncea ... See more keywords
Ric8 acts as a regulator of G-protein signaling required for nematode-trapping lifecycle of Arthrobotrys oligospora.
Sign Up to like & getrecommendations! Published in 2021 at "Environmental microbiology"
DOI: 10.1111/1462-2920.15735
Abstract: Resistance to inhibitors of cholinesterase 8 (Ric8) is a conserved guanine nucleotide exchange factor that is involved in the regulation of G-protein signaling in filamentous fungi. Here, we characterized an orthologous Ric8 (AoRic8) in Arthrobotrys… read more here.
Keywords: ric8 acts; regulator protein; protein signaling; acts regulator ... See more keywords
Abstract 5184: Expression and role of regulator of G-protein signing 5 in squamous cell carcinoma of the tongue
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Research"
DOI: 10.1158/1538-7445.am2018-5184
Abstract: Objective: Regulator of G-protein signing (RGS) 5 is a member of the RGS family and acts as GTPase-activating proteins for heterotorimeric G protein αsubunits, negatively regulating G-protein signaling. RGS5 was reportedly expressed in the heart,… read more here.
Keywords: regulator protein; carcinoma; cell carcinoma; squamous cell ... See more keywords
Cardiometabolic Consequences of Deleting the Regulator of G protein Signaling-2 (Rgs2) From Cells Expressing Agouti-Related Peptide or the ANG (Angiotensin) II Type 1A Receptor in Mice
Sign Up to like & getrecommendations! Published in 2022 at "Hypertension"
DOI: 10.1161/hypertensionaha.122.20169
Abstract: Background: RGS (regulator of G protein signaling) family members catalyze the termination of G protein signaling cascades. Single nucleotide polymorphisms in the RGS2 gene in humans have been linked to hypertension, preeclampsia, and anxiety disorders.… read more here.
Keywords: rgs2; regulator protein; mice; protein signaling ... See more keywords
Abstract 842: Protein kinase G - Regulator of G protein Signaling 2 Axis of Cardiac Myocytes Critically Determines Cardiac Performance in Early Cardiac Remodeling
Sign Up to like & getrecommendations! Published in 2019 at "Circulation Research"
DOI: 10.1161/res.125.suppl_1.842
Abstract: Introduction: Regulator of G protein signaling 2 (RGS2) is a negative regulator of G protein-coupled signaling, and is potentiated by cGMP-PKG. Our prior work using a global deletion model demonstrated the protective role for RGS2… read more here.
Keywords: protein; regulator protein; tac; cardiac remodeling ... See more keywords
A regulator of G protein signaling 5 marked subpopulation of vascular smooth muscle cells is lost during vascular disease
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0265132
Abstract: Vascular smooth muscle cell (VSMC) subpopulations relevant to vascular disease and injury repair have been depicted in healthy vessels and atherosclerosis profiles. However, whether VSMC subpopulation associated with vascular homeostasis exists in the healthy artery… read more here.
Keywords: vascular smooth; protein signaling; regulator protein; vascular disease ... See more keywords
CRISPR-Cas13-Mediated Knockdown of Regulator of G-Protein Signaling 8 (RGS8) Does Not Affect Purkinje Cell Dendritic Development
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.854273
Abstract: CRISPR-Cas13 technology is rapidly evolving as it is a very specific tool for RNA editing and interference. Since there are no significant off-target effects via the Cas13-mediated method, it is a promising tool for studying… read more here.
Keywords: regulator protein; cas13; crispr cas13; purkinje ... See more keywords
Effect of Regulator of G Protein Signaling Proteins on Bone
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.842421
Abstract: Regulator of G protein signaling (RGS) proteins are critical negative molecules of G protein-coupled receptor (GPCR) signaling, which mediates a variety of biological processes in bone homeostasis and diseases. The RGS proteins are divided into… read more here.
Keywords: regulator protein; bone; protein signaling; rgs proteins ... See more keywords