Transcriptional profiling identifies novel regulators of macrophage polarization
Sign Up to like & getrecommendations! Published in 2018 at "PLoS ONE"
DOI: 10.1371/journal.pone.0208602
Abstract: Macrophages are key inflammatory immune cells that display dynamic phenotypes and functions in response to their local microenvironment. Major advances have occurred in understanding the transcriptional, epigenetic, and functional differences in various macrophage subsets by… read more here.
Keywords: profiling; macrophage polarization; regulators macrophage; polarization ... See more keywords
MicroRNA: Dynamic Regulators of Macrophage Polarization and Plasticity
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2017.01062
Abstract: The ability of a healthy immune system to clear the plethora of antigens it encounters incessantly relies on the enormous plasticity displayed by the comprising cell types. Macrophages (MΦs) are crucial member of the mononuclear… read more here.
Keywords: regulators macrophage; polarization; microrna dynamic; dynamic regulators ... See more keywords
Context-enriched interactome powered by proteomics helps the identification of novel regulators of macrophage activation
Sign Up to like & getrecommendations! Published in 2018 at "eLife"
DOI: 10.7554/elife.37059
Abstract: The role of pro-inflammatory macrophage activation in cardiovascular disease (CVD) is a complex one amenable to network approaches. While an indispensible tool for elucidating the molecular underpinnings of complex diseases including CVD, the interactome is… read more here.
Keywords: context enriched; network; macrophage activation; regulators macrophage ... See more keywords