Systematic Identification of Regulators of Oxidative Stress Reveals Non-canonical Roles for Peroxisomal Import and the Pentose Phosphate Pathway.
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DOI: 10.1016/j.celrep.2020.01.013
Abstract: Reactive oxygen species (ROS) play critical roles in metabolism and disease, yet a comprehensive analysis of the cellular response to oxidative stress is lacking. To systematically identify regulators of oxidative stress, we conducted genome-wide Cas9/CRISPR and shRNA… read more here.
Keywords: phosphate pathway; regulators oxidative; pentose phosphate; import ... See more keywords