Novel regulators of PrPC biosynthesis revealed by genome-wide RNA interference
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DOI: 10.1371/journal.ppat.1010013
Abstract: The cellular prion protein PrPC is necessary for prion replication, and its reduction greatly increases life expectancy in animal models of prion infection. Hence the factors controlling the levels of PrPC may represent therapeutic targets… read more here.
Keywords: prpc; regulators prpc; rna interference; novel regulators ... See more keywords