Functional Genomics Approach Identifies Novel Signaling Regulators of TGFα Ectodomain Shedding
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DOI: 10.1158/1541-7786.mcr-17-0140
Abstract: Ectodomain shedding of cell-surface precursor proteins by metalloproteases generates important cellular signaling molecules. Of importance for disease is the release of ligands that activate the EGFR, such as TGFα, which is mostly carried out by… read more here.
Keywords: genomics approach; functional genomics; ectodomain shedding; egfr ligand ... See more keywords