Lipid metabolism regulatory activity and adverse effects of fungi-derived butyrolactone I
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DOI: 10.1080/14786419.2022.2122966
Abstract: Abstract Butyrolactone I (BTL-I), a butenolide compound isolated from land or marine-derived fungi, has been reported to show diverse activities. To further study the pharmaceutical potential of BTL-I, transcriptome and bioinformatics analysis of BTL-I treated… read more here.
Keywords: regulatory activity; butyrolactone; btl; adverse effects ... See more keywords
Dissecting the regulatory activity and sequence content of loci with exceptional numbers of transcription factor associations.
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DOI: 10.1101/gr.260463.119
Abstract: DNA associated proteins (DAPs) classically regulate gene expression by binding to regulatory loci such as enhancers or promoters. As expanding catalogs of genome-wide DAP binding maps reveal thousands of loci that, unlike the majority of… read more here.
Keywords: activity; regulatory activity; hot loci; sequence ... See more keywords
Functional characterization of enhancer activity during a long terminal repeat's evolution
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DOI: 10.1101/gr.276863.122
Abstract: Many transposable elements (TEs) contain transcription factor binding sites and are implicated as potential regulatory elements. However, TEs are rarely functionally tested for regulatory activity, which in turn limits our understanding of how TE regulatory… read more here.
Keywords: regulatory activity; functional characterization; activity; enhancer activity ... See more keywords
Removing the sporoderm from the sporoderm-broken spores of Ganoderma lucidum improves the anticancer and immune-regulatory activity of the water-soluble polysaccharide
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DOI: 10.3389/fnut.2022.1006127
Abstract: Plant-derived polysaccharides have demonstrated promising anti-cancer effects via immune-regulatory activity. The aim of the current study was to compare the chemical property and the anticancer effects of polysaccharides extracted from the sporoderm-removed spores of the… read more here.
Keywords: regulatory activity; immune regulatory; ganoderma lucidum; rsglp ... See more keywords