Rearrangement-mediated cis-regulatory alterations in advanced patient tumors reveal interactions with therapy
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DOI: 10.1016/j.celrep.2021.110023
Abstract: SUMMARY The global impact of somatic structural variants (SVs) on gene regulation in advanced tumors with complex treatment histories has been mostly uncharacterized. Here, using whole-genome and RNA sequencing from 570 recurrent or metastatic tumors,… read more here.
Keywords: mediated cis; rearrangement mediated; regulatory alterations; expression associations ... See more keywords