A functional LSD1 coregulator screen reveals a novel transcriptional regulatory cascade connecting R-loop homeostasis with epigenetic regulation
Sign Up to like & getrecommendations! Published in 2021 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkab180
Abstract: Abstract The lysine specific demethylase 1 (LSD1) plays a pivotal role in cellular differentiation by regulating the expression of key developmental genes in concert with different coregulatory proteins. This process is impaired in different cancer… read more here.
Keywords: novel transcriptional; ddx19a; regulatory cascade; coregulator ... See more keywords
A quorum-sensing regulatory cascade for siderophore-mediated iron homeostasis in Chromobacterium violaceum
Sign Up to like & getrecommendations! Published in 2024 at "mSystems"
DOI: 10.1128/msystems.01397-23
Abstract: ABSTRACT Iron is a transition metal used as a cofactor in many biochemical reactions. In bacteria, iron homeostasis involves Fur-mediated de-repression of iron uptake systems, such as the iron-chelating compounds siderophores. In this work, we… read more here.
Keywords: regulatory cascade; iron homeostasis; iron; violaceum ... See more keywords