Noncoding RNAs: New regulatory code in chondrocyte apoptosis and autophagy
Sign Up to like & getrecommendations! Published in 2020 at "Wiley Interdisciplinary Reviews: RNA"
DOI: 10.1002/wrna.1584
Abstract: Osteoarthritis (OA) is a bone and joint disease characterized by progressive cartilage degradation. In the face of global trends of population aging, OA is expected to become the fourth most common disabling disease by 2020.… read more here.
Keywords: new regulatory; regulatory code; apoptosis autophagy; chondrocyte ... See more keywords
Transcriptional regulation in plants: Using omics data to crack the cis-regulatory code.
Sign Up to like & getrecommendations! Published in 2021 at "Current opinion in plant biology"
DOI: 10.1016/j.pbi.2021.102058
Abstract: Innovative omics technologies, advanced bioinformatics, and machine learning methods are rapidly becoming integral tools for plant functional genomics, with tremendous recent advances made in this field. In transcriptional regulation, an initial lag in the accumulation… read more here.
Keywords: plant; regulatory code; omics data; cis regulatory ... See more keywords
metaRE R Package for Meta-Analysis of Transcriptome Data to Identify the cis-Regulatory Code behind the Transcriptional Reprogramming
Sign Up to like & getrecommendations! Published in 2020 at "Genes"
DOI: 10.3390/genes11060634
Abstract: At the molecular level, response to an external factor or an internal condition causes reprogramming of temporal and spatial transcription. When an organism undergoes physiological and/or morphological changes, several signaling pathways are activated simultaneously. Examples… read more here.
Keywords: response; cis regulatory; regulatory code; metare package ... See more keywords
Conserved noncoding transcription and core promoter regulatory code in early Drosophila development
Sign Up to like & getrecommendations! Published in 2017 at "eLife"
DOI: 10.7554/elife.29005
Abstract: Multicellular development is driven by regulatory programs that orchestrate the transcription of protein-coding and noncoding genes. To decipher this genomic regulatory code, and to investigate the developmental relevance of noncoding transcription, we compared genome-wide promoter… read more here.
Keywords: transcription; regulatory code; noncoding transcription; promoter ... See more keywords