Effects of Methylglyoxal on Intestinal Cells: Insights on Epigenetic Regulatory Enzymes.
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DOI: 10.1002/iub.70067
Abstract: Methylglyoxal (MGO) is endogenously produced under physiological conditions as a by‐product of glycolysis and by autooxidation of glucose and lipid peroxidation. The digestive system can also take up MGO from exogenous sources, especially from ultra‐processed… read more here.
Keywords: intestinal cells; regulatory enzymes; effects methylglyoxal; mgo ... See more keywords
Cholecalciferol decreases inflammation and improves vitamin D regulatory enzymes in lymphocytes in the uremic environment: A randomized controlled pilot trial
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DOI: 10.1371/journal.pone.0179540
Abstract: It has been reported that vitamin D regulates the immune system. However, whether vitamin D repletion modulates inflammatory responses in lymphocytes from dialysis patients is unclear. In the clinical trial, thirty-two (32) dialysis patients with… read more here.
Keywords: regulatory enzymes; trial; enzymes lymphocytes; expression ... See more keywords
Targeting Epigenetic Regulatory Enzymes for Cancer Therapeutics: Novel Small-Molecule Epidrug Development
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DOI: 10.3389/fonc.2022.848221
Abstract: Dysregulation of the epigenetic enzyme-mediated transcription of oncogenes or tumor suppressor genes is closely associated with the occurrence, progression, and prognosis of tumors. Based on the reversibility of epigenetic mechanisms, small-molecule compounds that target epigenetic… read more here.
Keywords: small molecule; target epigenetic; enzymes cancer; regulatory enzymes ... See more keywords