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Published in 2019 at "Hepatology"
DOI: 10.1002/hep.30559
Abstract: Nonalcoholic fatty liver disease (NAFLD) has become a worldwide epidemic. A large and growing unmet therapeutic need has inspired numerous studies in the field. Integrating the published genomic data available in the Gene Expression Omnibus…
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Keywords:
interferon regulatory;
regulatory factor;
irf6;
mice ... See more keywords
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Published in 2023 at "Journal of Medical Virology"
DOI: 10.1002/jmv.28521
Abstract: The binding of interferon (IFN) to its receptors leads to formation of IFN‐stimulated gene factor 3 (ISGF3) complex that activates the transcription of cellular IFN‐regulated genes. IFN regulatory factor 9 (IRF9, also called ISGF3γ or…
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Keywords:
canonical irf9;
primate specific;
irf9;
regulatory factor ... See more keywords
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Published in 2022 at "Journal of Basic Microbiology"
DOI: 10.1002/jobm.202200391
Abstract: The global regulatory factor LaeA has been shown to be involved in the biosynthesis of secondary metabolites in various fungi. In a previous work, we isolated an endophytic fungus from Artemisia annua, and its extract…
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Keywords:
global regulatory;
antitumor;
endophytic fungus;
alternaria alstroemeria ... See more keywords
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Published in 2018 at "Clinical Rheumatology"
DOI: 10.1007/s10067-018-4010-9
Abstract: Interferon regulatory factor 5 (IRF5) is a member of IRF family which induce signaling pathways and are involved in modulation of cell growth, differentiation, apoptosis, and immune system activity. Juvenile idiopathic arthritis (JIA) is an…
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Keywords:
irf5;
jia;
factor irf5;
interferon regulatory ... See more keywords
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Published in 2021 at "Molecular biology reports"
DOI: 10.1007/s11033-021-06260-w
Abstract: Interferon regulatory factor-1 (IRF-1) is a vertebrate transcription factor that plays significant roles in cell cycle regulation, anti-viral response, tumor suppression and immune response. High-level expression of recombinant IRF-1 at 37 °C leads to the formation…
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Keywords:
irf;
interferon regulatory;
factor irf;
regulatory factor ... See more keywords
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Published in 2018 at "Developmental and Comparative Immunology"
DOI: 10.1016/j.dci.2017.09.004
Abstract: ABSTRACT In mammals, IFN regulatory factor (IRF) 1 can activates cellular genes and promotes viral resistance against some DNA and RNA viruses. Most IRFs have been identified as critical regulators in the IFN responses in…
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Keywords:
duirf1;
regulatory factor;
positive regulator;
duck ... See more keywords
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Published in 2021 at "Developmental and comparative immunology"
DOI: 10.1016/j.dci.2021.104026
Abstract: In order to breed new birds with strong disease resistance, it is necessary to first understand the mechanism of avian antiviral response. Interferon regulatory factor 7 (IRF7) is not only a member of type I…
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Keywords:
infection;
regulatory factor;
interferon;
signaling pathway ... See more keywords
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Published in 2018 at "Gene"
DOI: 10.1016/j.gene.2018.08.080
Abstract: Interferon regulatory factor 5 (IRF5) is a key transcription factor involved in the control of the expression of pro-inflammatory cytokines and immune responses to infection, and multiple polymorphisms of the IFR5 gene have been shown…
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Keywords:
interferon regulatory;
regulatory factor;
community acquired;
factor ... See more keywords
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1
Published in 2019 at "Developmental biology"
DOI: 10.1016/j.ydbio.2018.10.010
Abstract: Electroporation-based assays were used to test whether the myogenic regulatory factor (MRF) of Ciona intestinalis (CiMRF) interferes with endogenous developmental programs, and to evaluate the importance of its unusual N-terminus for muscle development. We found…
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Keywords:
ciona;
regulatory factor;
mrf;
activity ... See more keywords
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Published in 2019 at "Nature microbiology"
DOI: 10.1038/s41564-019-0425-6
Abstract: Current models of cell-intrinsic immunity to RNA viruses centre on virus-triggered inducible antiviral responses initiated by RIG-I-like receptors or Toll-like receptors that sense pathogen-associated molecular patterns, and signal downstream through interferon regulatory factors (IRFs), transcription…
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Keywords:
basal expression;
rna viruses;
interferon regulatory;
rna ... See more keywords
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Published in 2022 at "Scientific reports"
DOI: 10.1038/s41598-022-09390-8
Abstract: Smad ubiquitination regulatory factor 2 (Smurf2) plays various roles in cancer progression. However, the correlation between Smurf2 and clinical outcomes has not been determined in patients diagnosed with colorectal cancer and colorectal liver metastases. We…
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Keywords:
cancer;
smad ubiquitination;
regulatory factor;
expression ... See more keywords