Decoding the Regulatory Logic of the Drosophila Male Stem Cell System.
Sign Up to like & getrecommendations! Published in 2018 at "Cell reports"
DOI: 10.1016/j.celrep.2018.08.013
Abstract: The niche critically controls stem cell behavior, but its regulatory input at the whole-genome level is poorly understood. We elucidated transcriptional programs of the somatic and germline lineages in the Drosophila testis and genome-wide binding profiles… read more here.
Keywords: decoding regulatory; logic drosophila; stem cell; regulatory logic ... See more keywords
The cis-regulatory logic underlying abdominal Hox-mediated repression versus activation of regulatory elements in Drosophila.
Sign Up to like & getrecommendations! Published in 2019 at "Developmental biology"
DOI: 10.1016/j.ydbio.2018.11.006
Abstract: During development diverse transcription factor inputs are integrated by cis-regulatory modules (CRMs) to yield cell-specific gene expression. Defining how CRMs recruit the appropriate combinations of factors to either activate or repress gene expression remains a… read more here.
Keywords: transcription; hox; cis regulatory; activation ... See more keywords
In silico analysis of the transcriptional regulatory logic of neuronal identity specification throughout the C. elegans nervous system
Sign Up to like & getrecommendations! Published in 2021 at "eLife"
DOI: 10.7554/elife.64906
Abstract: The generation of the enormous diversity of neuronal cell types in a differentiating nervous system entails the activation of neuron type-specific gene batteries. To examine the regulatory logic that controls the expression of neuron type-specific… read more here.
Keywords: system; neuronal identity; nervous system; regulatory logic ... See more keywords