Monocytes of newly diagnosed juvenile DM1 patients are prone to differentiate into regulatory IL-10+ M2 macrophages
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DOI: 10.1007/s12026-019-09072-0
Abstract: Alternatively activated macrophages (M2) exert anti-inflammatory effects and are crucial for keeping balance between protective and destructive cell-mediated immunity in healing phase of inflammation. Two members of the interferon regulatory factors family, IRF5 and IRF4,… read more here.
Keywords: dm1 patients; newly diagnosed; dm1; regulatory macrophages ... See more keywords
Regulatory Macrophages and Tolerogenic Dendritic Cells in Myeloid Regulatory Cell-Based Therapies
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DOI: 10.3390/ijms22157970
Abstract: Myeloid regulatory cell-based therapy has been shown to be a promising cell-based medicinal approach in organ transplantation and for the treatment of autoimmune diseases, such as type 1 diabetes, rheumatoid arthritis, Crohn’s disease and multiple… read more here.
Keywords: regulatory cell; myeloid regulatory; cell based; dendritic cells ... See more keywords