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Published in 2022 at "Viral immunology"
DOI: 10.1089/vim.2021.0211
Abstract: As the fifth pandemic in the 21st century, coronavirus 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become the most prominent global concern in the last 2 years. Variable manifestations characterize…
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Keywords:
role immune;
role;
immune regulatory;
infection ... See more keywords
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Published in 2018 at "Shock"
DOI: 10.1097/shk.0000000000001258
Abstract: BACKGROUND The complex host response to sepsis is incompletely understood. The aim of this investigation is to use leukocyte RNA sequencing to characterize biological functions, cellular pathways, and key regulatory molecules driving sepsis pathophysiology. METHODS…
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Keywords:
sepsis;
regulatory molecules;
response;
cellular pathways ... See more keywords
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Published in 2023 at "European journal of clinical investigation"
DOI: 10.1111/eci.14006
Abstract: INTRODUCTION Tocilizumab(TCZ) treatment is associated with dyslipidemia, including a rise in triglycerides through a mechanism poorly understood. Three molecules play key roles in the regulation of triglyceride metabolism: apolipoprotein C-III(ApoC-III), angiopoietin-like protein 4(ANGPLT4), and lipoprotein…
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Keywords:
metabolism;
tocilizumab;
tcz treatment;
regulatory molecules ... See more keywords