Outcomes in CLL patients with NOTCH1 regulatory pathway mutations
Sign Up to like & getrecommendations! Published in 2021 at "American Journal of Hematology"
DOI: 10.1002/ajh.26140
Abstract: All authors made substantial contributions to the (a) conception or design of the work; or the acquisition, analysis, or interpretation of data for the work; and (b) drafting the work or revising it critically for… read more here.
Keywords: patients notch1; work; notch1 regulatory; regulatory pathway ... See more keywords
Effect of panaxytriol on cytochrome P450 3A4 via the pregnane X receptor regulatory pathway
Sign Up to like & getrecommendations! Published in 2019 at "Phytotherapy Research"
DOI: 10.1002/ptr.6290
Abstract: Panaxytriol (PXT) is one of the major effective components of red ginseng and Shenmai injection. The present study aimed to explore the effect of PXT on cytochrome P450 3A4 (CYP3A4) based on the pregnane X… read more here.
Keywords: regulatory pathway; cyp3a4; hepg2 cells; hepg2 ... See more keywords
Recruitment of a Lineage-Specific Virulence Regulatory Pathway Promotes Intracellular Infection by a Plant Pathogen Experimentally Evolved into a Legume Symbiont
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Biology and Evolution"
DOI: 10.1093/molbev/msx165
Abstract: Ecological transitions between different lifestyles, such as pathogenicity, mutualism and saprophytism, have been very frequent in the course of microbial evolution, and often driven by horizontal gene transfer. Yet, how genomes achieve the ecological transition… read more here.
Keywords: pathogen; intracellular infection; virulence; regulatory pathway ... See more keywords
Toward A Regulatory Pathway for the Use of in Silico Trials in the CE Marking of Medical Devices
Sign Up to like & getrecommendations! Published in 2022 at "IEEE Journal of Biomedical and Health Informatics"
DOI: 10.1109/jbhi.2022.3198145
Abstract: In Silico Trials methodologies will play a growing and fundamental role in the development and de-risking of new medical devices in the future. While the regulatory pathway for Digital Patient and Personal Health Forecasting solutions… read more here.
Keywords: medical devices; silico trials; regulatory pathway; regulatory system ... See more keywords
KRAS Hijacks the miRNA Regulatory Pathway in Cancer
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/0008-5472.can-23-0296
Abstract: Abstract Extensive studies have focused on the misregulation of individual miRNAs in cancer. More recently, mutations in the miRNA biogenesis and processing machinery have been implicated in several malignancies. Such mutations can lead to global… read more here.
Keywords: mirna regulatory; hijacks mirna; kras hijacks; regulatory pathway ... See more keywords
A microRNA-24-to-secretagogin regulatory pathway mediates cholesterol-induced inhibition of insulin secretion
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Molecular Medicine"
DOI: 10.3892/ijmm.2019.4224
Abstract: Hypercholesterolemia is a key factor leading to β-cell dysfunction, but its underlying mechanisms remain unclear. Secretagogin (Scgn), a Ca2+ sensor protein that is expressed at high levels in the islets, has been shown to play… read more here.
Keywords: cell dysfunction; insulin secretion; cholesterol induced; regulatory pathway ... See more keywords