Signal Mechanism of the Protective Effect of Combined Preconditioning by Amtizole and Moderate Hypoxia
Sign Up to like & getrecommendations! Published in 2018 at "Bulletin of Experimental Biology and Medicine"
DOI: 10.1007/s10517-018-3981-5
Abstract: The content of regulatory proteins involved in adaptation to hypoxia and ischemia was studied in brain rat homogenate under conditions of normoxia and after bilateral ligation of the common carotid arteries. Preconditioning with amtizole in… read more here.
Keywords: regulatory proteins; signal mechanism; combined preconditioning; preconditioning amtizole ... See more keywords
Using Site Specific Fluorescent Probes to Examine Replication Fork Destabilization by Regulatory Proteins of the Bacteriophage T4 DNA Replication Complex
Sign Up to like & getrecommendations! Published in 2017 at "Biophysical Journal"
DOI: 10.1016/j.bpj.2016.11.1705
Abstract: The reconstituted T4 DNA replication complex serves as the simplest model system to examine the ‘core’ replication mechanisms of higher organisms. In this study we used site-specifically introduced fluorescent base analogues to track local conformational… read more here.
Keywords: replication fork; regulatory proteins; dna replication; replication complex ... See more keywords
Rho GTPase regulatory proteins in podocytes.
Sign Up to like & getrecommendations! Published in 2020 at "Kidney international"
DOI: 10.1016/j.kint.2020.08.035
Abstract: Rho-family of small GTPases (Rho GTPases) are the master regulators of the actin cytoskeleton and consist of 22 members. Previous studies implicated dysregulation of Rho GTPases in podocytes in the pathogenesis of proteinuric glomerular diseases.… read more here.
Keywords: regulatory proteins; rho gtpase; proteins podocytes; gtpase regulatory ... See more keywords
Deciphering Regulatory Proteins of Prenylated Protein via the FRET Technique Using Nitroso-Based Ene-Ligation and Sequential Azidation and Click Reaction.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c02662
Abstract: We report here the selective incorporations of nitroso species into a wide range of proteins targeting lysine residue(s). The corresponding azo functionalities were formed in a highly selective manner with excellent yields, displaying rather good… read more here.
Keywords: deciphering regulatory; regulatory proteins; via fret; click reaction ... See more keywords
Inhibitors Alter the Stochasticity of Regulatory Proteins to Force Cells to Switch to the Other State in the Bistable System
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-04596-7
Abstract: The cellular behaviors under the control of genetic circuits are subject to stochastic fluctuations, or noise. The stochasticity in gene regulation, far from a nuisance, has been gradually appreciated for its unusual function in cellular… read more here.
Keywords: state; regulatory proteins; stochasticity regulatory; stochasticity ... See more keywords
Altered transcriptional regulatory proteins in glioblastoma and YBX1 as a potential regulator of tumor invasion
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-47360-9
Abstract: We have studied differentially regulated nuclear proteome of the clinical tissue specimens of glioblastoma (GBM, WHO Grade IV) and lower grades of gliomas (Grade II and III) using high resolution mass spectrometry- based quantitative proteomics… read more here.
Keywords: potential regulator; regulatory proteins; ybx1 potential; invasion ... See more keywords
Eukaryotic-like phosphoprotein phosphatase (PPP) enzyme evolution: interactions with environmental toxins and regulatory proteins
Sign Up to like & getrecommendations! Published in 2023 at "Bioscience Reports"
DOI: 10.1042/bsr20230378
Abstract: Abstract Phosphoprotein phosphatases (PPPs) are a ubiquitous class of enzymes which dephosphorylate serine and threonine residues on substrate proteins involved in a wide variety of cellular processes. The active site of PPP enzymes are highly… read more here.
Keywords: environmental toxins; eukaryotic like; ppp; regulatory proteins ... See more keywords
Aurora B opposes PP1 function in mitosis by phosphorylating the conserved PP1-binding RVxF motif in PP1 regulatory proteins
Sign Up to like & getrecommendations! Published in 2018 at "Science Signaling"
DOI: 10.1126/scisignal.aai8669
Abstract: Phosphorylation within conserved motifs in regulatory subunits controls protein phosphatase 1 (PP1) holoenzyme assembly during mitosis. Yin and yang of mitotic phosphorylation Mitotic kinases promote cell cycle progression by targeting a large set of proteins… read more here.
Keywords: regulatory proteins; mitosis; pp1; pp1 regulatory ... See more keywords
Structural Domains of CIF3 Required for Interaction with Cytokinesis Regulatory Proteins and for Cytokinesis Initiation in Trypanosoma brucei
Sign Up to like & getrecommendations! Published in 2022 at "mSphere"
DOI: 10.1128/msphere.00047-22
Abstract: Cytokinesis is the final stage of cell division and is regulated by a signaling pathway conserved from yeast to humans. Cytokinesis in Trypanosoma brucei, an early-branching protozoan parasite causing human sleeping sickness, is regulated by… read more here.
Keywords: trypanosoma brucei; coiled coil; cytokinesis; regulatory proteins ... See more keywords
Regulation of Cell Cycle Regulatory Proteins by MicroRNAs in Uterine Leiomyoma
Sign Up to like & getrecommendations! Published in 2019 at "Reproductive Sciences"
DOI: 10.1177/1933719118768692
Abstract: The objective of this study was to determine whether miR-93, miR-29c, and miR-200c, which we previously reported to be downregulated in leiomyomas, target cell cycle regulatory proteins that influence cell proliferation. Based on TargetScan algorithm… read more here.
Keywords: regulatory proteins; cycle regulatory; mir; cell cycle ... See more keywords
Effect of Heme Oxygenase-1 Depletion on Complement Regulatory Proteins Expression in the Rat
Sign Up to like & getrecommendations! Published in 2022 at "Antioxidants"
DOI: 10.3390/antiox12010061
Abstract: Heme oxygenase has been implicated in the regulation of various immune responses including complement activation. Using a transgenic rat model of HO-1 depletion, the present study assessed the effect of HO-1 absence on the expression… read more here.
Keywords: complement; complement regulatory; heme oxygenase; regulatory proteins ... See more keywords