Articles with "regulatory system" as a keyword



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Transcriptional analysis of prsA and vraTS regulatory system in methicillin resistant Staphylococcus aureus against oxacillin stress.

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Published in 2021 at "Indian journal of medical microbiology"

DOI: 10.1016/j.ijmmb.2021.10.009

Abstract: PURPOSE The prsA and vraTSR regulatory systems play a unique role in methicillin resistance by modifying the peptidoglycan cell wall PBP2 and involving cell wall stress response in Staphylococcus aureus. This study was designed to… read more here.

Keywords: staphylococcus aureus; prsa; regulatory system; oxacillin stress ... See more keywords
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The reduced ARF regulatory system in Giardia intestinalis pre-dates the transition to parasitism in the lineage Fornicata.

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Published in 2021 at "International journal for parasitology"

DOI: 10.1016/j.ijpara.2021.02.004

Abstract: Giardia intestinalis is an enteric pathogen with an extremely modified membrane trafficking system, lacking canonical compartments such as the Golgi, endosomes, and intermediate vesicle carriers. By comparison the fornicate relatives of Giardia possess comparatively greater… read more here.

Keywords: regulatory system; giardia intestinalis; system; arf regulatory ... See more keywords
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Proteolysis and multimerization regulate signaling along the two-component regulatory system AdeRS

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Published in 2021 at "iScience"

DOI: 10.1016/j.isci.2021.102476

Abstract: Summary Bacterial two-component regulatory systems are ubiquitous environment-sensing signal transducers involved in pathogenesis and antibiotic resistance. The Acinetobacter baumannii two-component regulatory system AdeRS is made up of a sensor histidine kinase AdeS and a cognate… read more here.

Keywords: regulatory system; two component; component regulatory; system aders ... See more keywords
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Toward A Regulatory Pathway for the Use of in Silico Trials in the CE Marking of Medical Devices

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Published in 2022 at "IEEE Journal of Biomedical and Health Informatics"

DOI: 10.1109/jbhi.2022.3198145

Abstract: In Silico Trials methodologies will play a growing and fundamental role in the development and de-risking of new medical devices in the future. While the regulatory pathway for Digital Patient and Personal Health Forecasting solutions… read more here.

Keywords: medical devices; silico trials; regulatory pathway; regulatory system ... See more keywords
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Therapeutic Inhibition of Staphylococcus aureus ArlRS Two-Component Regulatory System Blocks Virulence

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Published in 2022 at "Antimicrobial Agents and Chemotherapy"

DOI: 10.1128/aac.00187-22

Abstract: Staphylococcus aureus is a common cause of severe infections, and its widespread antibiotic resistance necessitates search for alternative therapies, such as inhibition of virulence. As S. aureus produces multiple individual virulence factors, inhibition of an… read more here.

Keywords: staphylococcus aureus; inhibition; virulence; regulatory system ... See more keywords
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An evaluation of the Caribbean regulatory system centralized assessment process for medicines submitted 2017–2018 using the OpERA methodology

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Published in 2020 at "Journal of Pharmaceutical Policy and Practice"

DOI: 10.1186/s40545-020-00261-z

Abstract: Background The Caribbean Regulatory System is a centralized medicine assessment procedure established to serve the needs of the Member States of the CARICOM region. In order to better understand the effectiveness and efficiency of the… read more here.

Keywords: methodology; system; regulatory system; caribbean regulatory ... See more keywords