New insights into the activation of Radiation Desiccation Response regulon in Deinococcus radiodurans
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DOI: 10.1007/s12038-020-00123-5
Abstract: The highly radiation-resistant bacterium Deinococcus radiodurans responds to gamma radiation or desiccation through the coordinated expression of genes belonging to Radiation and Desiccation Resistance/Response (RDR) regulon. RDR regulon is operated through cis -acting sequence RDRM… read more here.
Keywords: radiation desiccation; regulon; rdr regulon; response ... See more keywords
An expanded role of the SNARE-containing regulon as it relates to the defense process that Glycine max has to Heterodera glycines
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DOI: 10.1080/17429145.2019.1622043
Abstract: ABSTRACT The defense regulon has been defined genetically in Arabidopsis thaliana to involve the syntaxin PENETRATION1 (PEN1), the secreted glucosidase (PEN2) and an ATP-binding cassette (ABC) transporter (PEN3). Experiments in Glycine max (soybean) have identified… read more here.
Keywords: defense; regulon; defense process; heterodera glycines ... See more keywords
RTNsurvival: an R/Bioconductor package for regulatory network survival analysis
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DOI: 10.1093/bioinformatics/btz229
Abstract: MOTIVATION Transcriptional networks are models that allow the biological state of cells or tumours to be described. Such networks consist of connected regulatory units known as regulons, each comprised of a regulator and its targets.… read more here.
Keywords: package; network; rtnsurvival bioconductor; regulon ... See more keywords
Exposure of Shewanella oneidensis MR-1 to Sublethal Doses of Ionizing Radiation Triggers Short-Term SOS Activation and Longer-Term Prophage Activation
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DOI: 10.1128/aem.01716-22
Abstract: The bacterial minimum threshold of sensitivity to ionizing radiation (IR) is poorly understood, which hinders our understanding of how living systems recover from the doses of IR experienced in medical, industrial, and off-world environments. Using… read more here.
Keywords: prophage; regulon; activation; ionizing radiation ... See more keywords
Mutations of the Bacillus subtilis YidC1 (SpoIIIJ) insertase alleviate stress associated with σM-dependent membrane protein overproduction
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DOI: 10.1371/journal.pgen.1008263
Abstract: In Bacillus subtilis, the extracytoplasmic function σ factor σM regulates cell wall synthesis and is critical for intrinsic resistance to cell wall targeting antibiotics. The anti-σ factors YhdL and YhdK form a complex that restricts… read more here.
Keywords: regulon; yidc1 spoiiij; stress; bacillus subtilis ... See more keywords
Comprehensive Characterization of the Regulatory Landscape of Adrenocortical Carcinoma: Novel Transcription Factors and Targets Associated with Prognosis
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DOI: 10.3390/cancers14215279
Abstract: Simple Summary Adult adrenocortical carcinoma (ACC) is a rare and aggressive tumor in adults, usually associated with excessive steroid secretion. It is highly metastatic and has few therapeutic options and a poor prognosis. Here, we… read more here.
Keywords: prognosis; regulon; transcription factors; adrenocortical carcinoma ... See more keywords