LAUSR

Reimagining Druggability Using Chemoproteomic Platforms.

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0 Published in 2021 at "Accounts of chemical research"

DOI: 10.1021/acs.accounts.1c00065

Abstract: ConspectusOne of the biggest bottlenecks in modern drug discovery efforts is in tackling the undruggable proteome. Currently, over 85% of the proteome is still considered undruggable because most proteins lack well-defined binding pockets that can… read more here.

Keywords: chemoproteomic platforms; undruggable proteome; therapeutic modalities; reimagining druggability ... See more keywords