Does eIF3 promote reinitiation after translation of short upstream ORFs also in mammalian cells?
Sign Up to like & getrecommendations! Published in 2017 at "RNA Biology"
DOI: 10.1080/15476286.2017.1353863
Abstract: ABSTRACT Reinitiation after translation of short upstream ORFs (uORFs) represents one of the means of regulation of gene expression on the mRNA-specific level in response to changing environmental conditions. Over the years it has been… read more here.
Keywords: reinitiation translation; reinitiation; translation short; translation ... See more keywords
Premature Termination Codon in 5′ Region of Desmoplakin and Plakoglobin Genes May Escape Nonsense-Mediated Decay through the Reinitiation of Translation
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23020656
Abstract: Arrhythmogenic cardiomyopathy is a heritable heart disease associated with desmosomal mutations, especially premature termination codon (PTC) variants. It is known that PTC triggers the nonsense-mediated decay (NMD) mechanism. It is also accepted that PTC in… read more here.
Keywords: premature termination; region; termination codon; reinitiation ... See more keywords