LAUSR

About LAUSR
Donate
Contact Us

Follow us:

You are not signed in:

Sign Up!


   Articles with "reinstatement cocaine" as a keyword



Photo by neom from unsplash

Dynamic CRMP2 Regulation of CaV2.2 in the Prefrontal Cortex Contributes to the Reinstatement of Cocaine Seeking

Sign Up to like & get
recommendations! Published in 2019 at "Molecular Neurobiology"

DOI: 10.1007/s12035-019-01711-9

Abstract: Cocaine addiction remains a major health concern with limited effective treatment options. A better understanding of mechanisms underlying relapse may help inform the development of new pharmacotherapies. Emerging evidence suggests that collapsin response mediator protein… read more here.

Keywords: crmp2; cocaine seeking; reinstatement cocaine; cocaine ... See more keywords
Photo by neom from unsplash

(-)-Stepholidine reduces cue-induced reinstatement of cocaine seeking and cocaine self-administration in rats.

Sign Up to like & get
recommendations! Published in 2018 at "Drug and alcohol dependence"

DOI: 10.1016/j.drugalcdep.2018.04.030

Abstract: BACKGROUND Dopamine receptors are implicated in cocaine reward and seeking. We hypothesize that (-)-stepholidine, a dopamine D1/D2/D3 multi-receptor agent, would be effective in reducing cocaine reward and seeking in an animal model. We investigated the… read more here.

Keywords: cue induced; cue; cocaine seeking; reinstatement cocaine ... See more keywords
Photo from wikipedia

Mirtazapine impairs acquisition and reinstatement of cocaine‐induced place preference in rats

Sign Up to like & get
recommendations! Published in 2018 at "European Journal of Pharmacology"

DOI: 10.1016/j.ejphar.2017.12.033

Abstract: ABSTRACT Exposure to cues previously associated with drug use and the environment can trigger intense craving and drug‐seeking, often leading to relapse in individuals with substance use disorders. Several studies suggest that the decrease in… read more here.

Keywords: cocaine; preference; reinstatement cocaine; acquisition reinstatement ... See more keywords
Photo by neom from unsplash

Perineuronal nets in the lateral hypothalamus area regulate cue-induced reinstatement of cocaine-seeking behavior

Sign Up to like & get
recommendations! Published in 2018 at "Neuropsychopharmacology"

DOI: 10.1038/s41386-018-0212-8

Abstract: We previously reported that a small, circumscribed region of the lateral hypothalamus, the anterior dorsal region (LHAad), stains heavily for PNNs and dense extracellular matrix (PNNs/ECM) with Wisteria floribunda agglutinin (WFA), and critically contributes to… read more here.

Keywords: cue induced; seeking behavior; reinstatement cocaine; cocaine ... See more keywords
Photo from wikipedia

CB1R activation in nucleus accumbens core promotes stress-induced reinstatement of cocaine seeking by elevating extracellular glutamate in a drug-paired context

Sign Up to like & get
recommendations! Published in 2021 at "Scientific Reports"

DOI: 10.1038/s41598-021-92389-4

Abstract: Preclinical models of stress-induced relapse to drug use have shown that the dysregulation of glutamatergic transmission within the nucleus accumbens (NA) contributes notably to the reinstatement of cocaine-seeking behavior in rodents. In this sense, there… read more here.

Keywords: cb1r; extracellular glutamate; stress induced; reinstatement cocaine ... See more keywords