Clofarabine, cytarabine, and mitoxantrone in refractory/relapsed acute myeloid leukemia: High response rates and effective bridge to allogeneic hematopoietic stem cell transplantation
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Medicine"
DOI: 10.1002/cam4.2865
Abstract: Clofarabine is active in refractory/relapsed acute myeloid leukemia (AML). In this phase 2 study, we treated 18‐ to 65‐year‐old AML patients refractory to first‐line 3 + 7 daunorubicin/cytarabine induction or relapsing after 3 + 7… read more here.
Keywords: allo hsct; relapsed acute; clofarabine; refractory relapsed ... See more keywords
Anti‐CLL1‐based CAR T‐cells with 4‐1‐BB or CD28/CD27 stimulatory domains in treating childhood refractory/relapsed acute myeloid leukemia
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DOI: 10.1002/cam4.5916
Abstract: Though the efficacy of anti C‐type lectin‐like molecule‐1 (CLL1) CAR T‐cells in refractory/relapsed acute myeloid leukemia (R/R‐AML) have been occasionally reported, the influence of co‐stimulatory domain CAR T‐cells is not investigated so far. read more here.
Keywords: refractory relapsed; myeloid leukemia; car; acute myeloid ... See more keywords
Second allogeneic hematopoietic cell transplantation enables long-term disease-free survival in relapsed acute leukemia
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DOI: 10.1007/s00277-018-3454-y
Abstract: Allogeneic hematopoietic cell transplantation (HCT) is the treatment of choice for high-risk myeloid and lymphoid leukemias. Relapse after allogeneic HCT is associated with a dismal prognosis and further therapeutic options are limited. One potential curative… read more here.
Keywords: second allogeneic; relapsed acute; hct; survival ... See more keywords
Prognostic relevance of treatment deviations in children with relapsed acute lymphoblastic leukemia who were treated in the ALL-REZ BFM 2002 study
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DOI: 10.1038/s41375-024-02474-6
Abstract: Relapsed Acute Lymphoblastic Leukemia (ALL) is among the most common causes of cancer-associated deaths in children. However, little is known about the implications of deviations from ALL treatment protocols on survival rates. The present study… read more here.
Keywords: treatment; acute lymphoblastic; lymphoblastic leukemia; relapsed acute ... See more keywords
Fractionated gemtuzumab ozogamicin in association with high dose chemotherapy: a bridge to allogeneic stem cell transplantation in refractory and relapsed acute myeloid leukemia
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DOI: 10.1038/s41409-019-0690-2
Abstract: Optimization of the salvage regimen is required to improve prognosis in primary refractory or relapsed acute myeloid leukemia (AML). In fit patients, a bridge to allogeneic transplant is the primary purpose of salvage. We tested… read more here.
Keywords: relapsed acute; bridge allogeneic; refractory relapsed; salvage ... See more keywords
Rhabdomyolysis Following Initiation of Posaconazole Use for Antifungal Prophylaxis in a Patient With Relapsed Acute Myeloid Leukemia
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DOI: 10.1177/2324709617690747
Abstract: Posaconazole is a commonly used medication for antifungal prophylaxis in patients with high-risk acute leukemia, such as acute myeloid leukemia. Despite clinical data that show that posaconazole is superior to other antifungal prophylaxis medications, posaconazole… read more here.
Keywords: relapsed acute; myeloid leukemia; antifungal prophylaxis; prophylaxis ... See more keywords
Second Transplants for Relapsed Acute Leukemia: Real World Experience from Argentina
Sign Up to like & getrecommendations! Published in 2018 at "Blood"
DOI: 10.1182/blood-2018-99-119909
Abstract: INTRODUCTION Acute leukemia relapsing after allogeneic stem cell transplantation (AlloSCT) is usually associated with dismal prognosis. Treatment options in this population remain limited. We evaluated the outcomes of second AlloSCT in patients with acute leukemia… read more here.
Keywords: relapsed acute; maintenance; treatment; transplant ... See more keywords
A childhood-onset intestinal toxemia botulism during chemotherapy for relapsed acute leukemia
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DOI: 10.1186/s12941-017-0240-y
Abstract: BackgroundBotulism is a potentially fatal infection characterized by progressive muscle weakness, bulbar paralysis, constipation and other autonomic dysfunctions. A recent report suggested that cancer chemotherapy might increase the risk for the intestinal toxemia botulism in… read more here.
Keywords: chemotherapy; relapsed acute; botulism; intestinal toxemia ... See more keywords
Erratum for: Salvage treatment for refractory or relapsed acute myeloid leukemia: a 10-year single-center experience
Sign Up to like & getrecommendations! Published in 2020 at "Clinics"
DOI: 10.6061/clinics/2020/e1566err
Abstract: [This corrects the article doi: 10.6061/clinics/2020/e1566]. read more here.
Keywords: relapsed acute; refractory relapsed; salvage treatment; treatment refractory ... See more keywords