A Common Polymorphism in a Williams Syndrome Gene Predicts Amygdala Reactivity and Extraversion in Healthy Adults
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DOI: 10.1016/j.biopsych.2015.12.007
Abstract: BACKGROUND Williams syndrome (WS), a genetic disorder resulting from hemizygous microdeletion of chromosome 7q11.23, has emerged as a model for identifying the genetic architecture of socioemotional behavior. Common polymorphisms in GTF2I, which is found within… read more here.
Keywords: amygdala reactivity; threat related; reactivity; williams syndrome ... See more keywords
Replication in Imaging Genetics: The Case of Threat-Related Amygdala Reactivity
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DOI: 10.1016/j.biopsych.2017.11.010
Abstract: BACKGROUND Low replication rates are a concern in most, if not all, scientific disciplines. In psychiatric genetics specifically, targeting intermediate brain phenotypes, which are more closely associated with putative genetic effects, was touted as a… read more here.
Keywords: amygdala reactivity; genetics; threat related; replication ... See more keywords
An earlier time of scan is associated with greater threat-related amygdala reactivity
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DOI: 10.1093/scan/nsx057
Abstract: Abstract Time-dependent variability in mood and anxiety suggest that related neural phenotypes, such as threat-related amygdala reactivity, may also follow a diurnal pattern. Here, using data from 1,043 young adult volunteers, we found that threat-related… read more here.
Keywords: related amygdala; amygdala reactivity; time; threat related ... See more keywords