Reversion Mutations with Clinical Use of PARP Inhibitors: Many Genes, Many Versions.
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DOI: 10.1158/2159-8290.cd-17-0734
Abstract: Reversion mutations associated with PARP inhibitor resistance have been identified in tumors with RAD51C, RAD51D, and PALB2 as well as BRCA1 and BRCA2 mutations. Multiple different reversion mutations can occur in a single patient, and… read more here.
Keywords: parp inhibitors; clinical use; use parp; related article ... See more keywords