Arterial Stiffness May Predict Subsequent Cancer Therapy-Related Cardiac Dysfunction in Breast Cancer Patients
Sign Up to like & getrecommendations! Published in 2024 at "Cardiovascular Toxicology"
DOI: 10.1007/s12012-024-09841-w
Abstract: Cancer therapy-related cardiac dysfunction (CTRCD) is still a serious problem. Existing risk scores are insufficient for risk classification, especially in low and medium-risk patients. This study aims to evaluate if arterial stiffness (AS) measurement, which… read more here.
Keywords: cancer; risk; dysfunction; related cardiac ... See more keywords
Melatonin: Protection against age-related cardiac pathology
Sign Up to like & getrecommendations! Published in 2017 at "Ageing Research Reviews"
DOI: 10.1016/j.arr.2016.11.007
Abstract: Aging is a complex and progressive process that involves physiological and metabolic deterioration in every organ and system. Cardiovascular diseases are one of the most common causes of mortality and morbidity among elderly subjects worldwide.… read more here.
Keywords: age related; melatonin protection; related cardiac; pathology ... See more keywords
Bioinformatics analysis of non-synonymous variants in the KLF genes related to cardiac diseases.
Sign Up to like & getrecommendations! Published in 2018 at "Gene"
DOI: 10.1016/j.gene.2018.01.085
Abstract: Kruppel-like Factors (KLF) are responsible for regulating many genes involved in physiological and pathological processes. They are characterized by three conserved zinc-fingers in the DNA-binding domain, wherein mutations could affect the binding efficiency and transcription… read more here.
Keywords: related cardiac; cardiac diseases; bioinformatics analysis; synonymous variants ... See more keywords
Fibronectin type III domain‐containing 5 improves aging‐related cardiac dysfunction in mice
Sign Up to like & getrecommendations! Published in 2022 at "Aging Cell"
DOI: 10.1111/acel.13556
Abstract: Aging is an important risk factor for cardiovascular diseases, and aging‐related cardiac dysfunction serves as a major determinant of morbidity and mortality in elderly populations. Our previous study has identified fibronectin type III domain‐containing 5… read more here.
Keywords: dysfunction; cardiac dysfunction; domain; related cardiac ... See more keywords
Assessment of cancer therapy‐related cardiac dysfunction in breast cancer women using a new speckle tracking echocardiography index: The GAVS
Sign Up to like & getrecommendations! Published in 2024 at "Echocardiography"
DOI: 10.1111/echo.15881
Abstract: Recently, peak atrial longitudinal strain (PALS) has emerged as a possible predictor of Cancer therapy‐related cardiac dysfunction (CTRCD) in cancer patients (CP), in addition to left ventricular global longitudinal strain (GLS). Thus, considering the link… read more here.
Keywords: cardiac dysfunction; cancer; related cardiac; therapy related ... See more keywords
Relationship between regional left ventricular dysfunction and cancer-therapy-related cardiac dysfunction
Sign Up to like & getrecommendations! Published in 2020 at "Heart"
DOI: 10.1136/heartjnl-2019-316339
Abstract: Objective The aim of our study was to assess the association between risk of cancer-therapy-related cardiac dysfunction (CTRCD) after first follow-up and the difference in echocardiographic measures from baseline to follow-up. Methods We retrospectively enrolled… read more here.
Keywords: therapy related; related cardiac; ctrcd; dysfunction ... See more keywords
Geniposide Protects against Obesity-Related Cardiac Injury through AMPKα- and Sirt1-Dependent Mechanisms
Sign Up to like & getrecommendations! Published in 2018 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2018/6053727
Abstract: Our previous study found that geniposide, an agonist of glucagon-like peptide-1 receptor (GLP-1R), protected against cardiac hypertrophy via the activation of AMP-activated protein kinase α (AMPKα). However, the effects of geniposide on obesity-related cardiac injury… read more here.
Keywords: related cardiac; obesity related; cardiac injury; obesity ... See more keywords
Role of GLP-1 Receptor Agonists in Managing Cancer Therapy-Related Cardiac Dysfunction.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of the American Heart Association"
DOI: 10.1161/jaha.125.040919
Abstract: BACKGROUND Current anticancer treatments can result in cancer therapy-related cardiac dysfunction (CTRCD). While glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have demonstrated cardioprotective properties, their role in CTRCD has not been previously explored. METHODS This retrospective… read more here.
Keywords: cardiac dysfunction; cancer; therapy; related cardiac ... See more keywords
Mitochondrial network remodeling of the diabetic heart: implications to ischemia related cardiac dysfunction
Sign Up to like & getrecommendations! Published in 2024 at "Cardiovascular Diabetology"
DOI: 10.1186/s12933-024-02357-1
Abstract: Mitochondria play a central role in cellular energy metabolism, and their dysfunction is increasingly recognized as a critical factor in the pathogenesis of diabetes-related cardiac pathophysiology, including vulnerability to ischemic events that culminate in myocardial… read more here.
Keywords: diabetic heart; mitochondrial network; heart; dysfunction ... See more keywords
Detecting subclinical anthracycline therapy-related cardiac dysfunction in patients attending Uganda Cancer Institute.
Sign Up to like & getrecommendations! Published in 2022 at "Future oncology"
DOI: 10.2217/fon-2022-0116
Abstract: Aims: To investigate the incidence of anthracycline therapy-related cardiac dysfunction (ATRCD) and its predictors among Ugandan cancer patients. Patients & methods: The study recruited 207 cancer patients who were followed for 6 months after ending… read more here.
Keywords: anthracycline therapy; related cardiac; therapy; therapy related ... See more keywords
Risk stratification in transthyretin-related cardiac amyloidosis
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2023.1151803
Abstract: Transthyretin related cardiac amyloidosis (TTR-CA) is an infiltrative cardiomyopathy that cause heart failure with preserved ejection fraction, mainly in aging people. Due to the introduction of a non invasive diagnostic algorithm, this disease, previously considered… read more here.
Keywords: transthyretin related; cardiac amyloidosis; risk stratification; related cardiac ... See more keywords